ADGC Publications

Found 23 results
Filters: Keyword is Genetic Predisposition to Disease and Author is Pericak-Vance, Margaret A  [Clear All Filters]
2022
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SEun, Bush WS, Engelman CD et al..  2022.  Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.. Brain. 145(7):2541-2554.
2021
Kunkle BW, Schmidt M, Klein H-U, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD et al..  2021.  Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.. JAMA Neurol. 78(1):102-113.
2019
Gardner OK, Wang L, Van Booven D, Whitehead PL, Hamilton-Nelson KL, Adams LD, Starks TD, Hofmann NK, Vance JM, Cuccaro ML et al..  2019.  RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways.. Hum Mol Genet. 28(18):3053-3061.
2017
Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S et al..  2017.  Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants.. PLoS One. 12(10):e0185777.
Huang K-L, Marcora E, Pimenova AA, Di Narzo AF, Kapoor M, Jin SChih, Harari O, Bertelsen S, Fairfax BP, Czajkowski J et al..  2017.  A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.. Nat Neurosci. 20(8):1052-1061.
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MVictoria, Budde J et al..  2017.  Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.. Acta Neuropathol. 133(5):839-856.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK et al..  2017.  Transethnic genome-wide scan identifies novel Alzheimer's disease loci.. Alzheimers Dement. 13(7):727-738.
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD et al..  2017.  Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.. Alzheimers Dement. 13(2):119-129.
2016
Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH et al..  2016.  Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.. Alzheimers Dement. 12(1):2-10.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML et al..  2016.  Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.. Alzheimers Dement. 12(3):233-43.
2015
Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA et al..  2015.  Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.. Alzheimers Dement. 11(12):1397-1406.
2014
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YSon, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang L-S et al..  2014.  Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA Neurol. 71(11):1394-404.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel J-P, Younkin SG et al..  2014.  Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.. PLoS Genet. 10(9):e1004606.
Jun G, Asai H, Zeldich E, Drapeau E, Chen CD, Chung J, Park J-H, Kim S, Haroutunian V, Foroud T et al..  2014.  PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.. Ann Neurol. 76(3):379-92.
2013
Nuytemans K, Bademci G, Kohli MM, Beecham GW, Wang L-S, Young JI, Nahab F, Martin ER, Gilbert JR, Benatar M et al..  2013.  C9ORF72 intermediate repeat copies are a significant risk factor for Parkinson disease.. Ann Hum Genet. 77(5):351-63.
Kohli MA, John-Williams K, Rajbhandary R, Naj A, Whitehead P, Hamilton K, Carney RM, Wright C, Crocco E, Gwirtzman HE et al..  2013.  Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians.. Neurobiol Aging. 34(5):1519.e5-12.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BNarayan, Wang L-S, Valladares O, Lin C-F, Larson EB, Graff-Radford NR et al..  2013.  Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.. JAMA. 309(14):1483-92.
2012
Zou F, Chai HSeng, Younkin CS, Allen M, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.. PLoS Genet. 8(6):e1002707.
Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS et al..  2012.  Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.. Nat Genet. 44(12):1349-54.
Jun G, Vardarajan BN, Buros J, Yu C-E, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL et al..  2012.  Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.. Arch Neurol. 69(10):1270-9.
Coppola G, Chinnathambi S, Lee JJiYong, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R et al..  2012.  Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.. Hum Mol Genet. 21(15):3500-12.
Allen M, Zou F, Chai HSeng, Younkin CS, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Novel late-onset Alzheimer disease loci variants associate with brain gene expression.. Neurology. 79(3):221-8.
2011
Naj AC, Jun G, Beecham GW, Wang L-S, Vardarajan BNarayan, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK et al..  2011.  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.. Nat Genet. 43(5):436-41.