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Found 12 results
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Genome-Wide Association Study
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Author
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Naj, Adam C
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2022
Kuksa PP
,
Liu C-L
,
Fu W
,
Qu L
,
Zhao Y
,
Katanic Z
,
Clark K
,
Kuzma AB
,
Ho P-C
,
Tzeng K-T
et al.
. 2022.
Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.
.
J Alzheimers Dis. 86(1):461-477.
Holstege H
,
Hulsman M
,
Charbonnier C
,
Grenier-Boley B
,
Quenez O
,
Grozeva D
,
van Rooij JGJ
,
Sims R
,
Ahmad S
,
Amin N
et al.
. 2022.
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.
.
Nat Genet. 54(12):1786-1794.
Heath L
,
Earls JC
,
Magis AT
,
Kornilov SA
,
Lovejoy JC
,
Funk CC
,
Rappaport N
,
Logsdon BA
,
Mangravite LM
,
Kunkle BW
et al.
. 2022.
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
.
Sci Rep. 12(1):6117.
2021
Chen H-H
,
Petty LE
,
Sha J
,
Zhao Y
,
Kuzma A
,
Valladares O
,
Bush W
,
Naj AC
,
Gamazon ER
,
Below JE
. 2021.
Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci.
.
Transl Psychiatry. 11(1):618.
Kunkle BW
,
Schmidt M
,
Klein H-U
,
Naj AC
,
Hamilton-Nelson KL
,
Larson EB
,
Evans DA
,
De Jager PL
,
Crane PK
,
Buxbaum JD
et al.
. 2021.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
.
JAMA Neurol. 78(1):102-113.
2017
Naj AC
,
Schellenberg GD
. 2017.
Genomic variants, genes, and pathways of Alzheimer's disease: An overview.
.
Am J Med Genet B Neuropsychiatr Genet. 174(1):5-26.
2014
Naj AC
,
Jun G
,
Reitz C
,
Kunkle BW
,
Perry W
,
Park YSon
,
Beecham GW
,
Rajbhandary RA
,
Hamilton-Nelson KL
,
Wang L-S
et al.
. 2014.
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
.
JAMA Neurol. 71(11):1394-404.
Beecham GW
,
Hamilton K
,
Naj AC
,
Martin ER
,
Huentelman M
,
Myers AJ
,
Corneveaux JJ
,
Hardy J
,
Vonsattel J-P
,
Younkin SG
et al.
. 2014.
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
.
PLoS Genet. 10(9):e1004606.
Ramirez A
,
van der Flier WM
,
Herold C
,
Ramonet D
,
Heilmann S
,
Lewczuk P
,
Popp J
,
Lacour A
,
Drichel D
,
Louwersheimer E
et al.
. 2014.
SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.
.
Hum Mol Genet. 23(24):6644-58.
2013
Lin C-F
,
Naj AC
,
Wang L-S
. 2013.
Analyzing copy number variation using SNP array data: protocols for calling CNV and association tests.
.
Curr Protoc Hum Genet. 79:Unit1.27..
2011
Naj AC
,
Jun G
,
Beecham GW
,
Wang L-S
,
Vardarajan BNarayan
,
Buros J
,
Gallins PJ
,
Buxbaum JD
,
Jarvik GP
,
Crane PK
et al.
. 2011.
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
.
Nat Genet. 43(5):436-41.
2010
Jun G
,
Naj AC
,
Beecham GW
,
Wang L-S
,
Buros J
,
Gallins PJ
,
Buxbaum JD
,
Ertekin-Taner N
,
M Fallin D
,
Friedland R
et al.
. 2010.
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
.
Arch Neurol. 67(12):1473-84.