ADGC Publications

Found 18 results
Filters: Keyword is Humans and Author is Naj, Adam C  [Clear All Filters]
2022
Kuksa PP, Liu C-L, Fu W, Qu L, Zhao Y, Katanic Z, Clark K, Kuzma AB, Ho P-C, Tzeng K-T et al..  2022.  Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.. J Alzheimers Dis. 86(1):461-477.
Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N et al..  2022.  Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.. Nat Genet. 54(12):1786-1794.
Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW et al..  2022.  Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.. Sci Rep. 12(1):6117.
2021
Chen H-H, Petty LE, Sha J, Zhao Y, Kuzma A, Valladares O, Bush W, Naj AC, Gamazon ER, Below JE.  2021.  Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci.. Transl Psychiatry. 11(1):618.
Kunkle BW, Schmidt M, Klein H-U, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD et al..  2021.  Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.. JAMA Neurol. 78(1):102-113.
2017
Kunkle BW, Vardarajan BN, Naj AC, Whitehead PL, Rolati S, Slifer S, Carney RM, Cuccaro ML, Vance JM, Gilbert JR et al..  2017.  Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.. JAMA Neurol. 74(9):1113-1122.
Naj AC, Schellenberg GD.  2017.  Genomic variants, genes, and pathways of Alzheimer's disease: An overview.. Am J Med Genet B Neuropsychiatr Genet. 174(1):5-26.
2016
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW et al..  2016.  The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.. Neurobiol Aging. 41:115-121.
2015
Wang L-S, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JDGonzalez, Cannon-Albright L, Baldwin CT, Zetterberg H et al..  2015.  Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA Neurol. 72(2):209-16.
Nelson PT, Wang W-X, Partch AB, Monsell SE, Valladares O, Ellingson SR, Wilfred BR, Naj AC, Wang L-S, Kukull WA et al..  2015.  Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.. J Neuropathol Exp Neurol. 74(1):75-84.
2014
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YSon, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang L-S et al..  2014.  Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA Neurol. 71(11):1394-404.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel J-P, Younkin SG et al..  2014.  Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.. PLoS Genet. 10(9):e1004606.
Carney RM, Kohli MA, Kunkle BW, Naj AC, Gilbert JR, Züchner S, Pericak-Vance MA.  2014.  Parkinsonism and distinct dementia patterns in a family with the MAPT R406W mutation.. Alzheimers Dement. 10(3):360-5.
Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E et al..  2014.  SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.. Hum Mol Genet. 23(24):6644-58.
2013
Lin C-F, Naj AC, Wang L-S.  2013.  Analyzing copy number variation using SNP array data: protocols for calling CNV and association tests.. Curr Protoc Hum Genet. 79:Unit1.27..
Stutzbach LD, Xie SX, Naj AC, Albin R, Gilman S, M Y Lee V, Trojanowski JQ, Devlin B, Schellenberg GD.  2013.  The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.. Acta Neuropathol Commun. 1:31.
2011
Naj AC, Jun G, Beecham GW, Wang L-S, Vardarajan BNarayan, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK et al..  2011.  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.. Nat Genet. 43(5):436-41.
2010
Jun G, Naj AC, Beecham GW, Wang L-S, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, M Fallin D, Friedland R et al..  2010.  Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.. Arch Neurol. 67(12):1473-84.