ADGC Publications

Found 21 results
Filters: Author is Saykin, Andrew J  [Clear All Filters]
2023
Chung J, Sahelijo N, Maruyama T, Hu J, Panitch R, Xia W, Mez J, Stein TD, Saykin AJ, Takeyama H et al..  2023.  Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles.. Alzheimers Dement.
Kang M, Ang TFang Alvin, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi S-E et al..  2023.  A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.. Mol Neurodegener. 18(1):40.
2022
Shade LMp, Katsumata Y, Hohman TJ, Nho K, Saykin AJ, Mukherjee S, Boehme KL, Kauwe JSk, Farrer LA, Schellenberg GD et al..  2022.  Genome-wide association study of brain arteriolosclerosis.. J Cereb Blood Flow Metab. 42(8):1437-1450.
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SEun, Bush WS, Engelman CD et al..  2022.  Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.. Brain. 145(7):2541-2554.
2021
Kunkle BW, Schmidt M, Klein H-U, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD et al..  2021.  Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.. JAMA Neurol. 78(1):102-113.
2020
Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J et al..  2020.  Genetic variants and functional pathways associated with resilience to Alzheimer's disease.. Brain. 143(8):2561-2575.
Sherva R, Gross A, Mukherjee S, Koesterer R, Amouyel P, Bellenguez C, Dufouil C, Bennett DA, Chibnik L, Cruchaga C et al..  2020.  Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.. Alzheimers Dement. 16(8):1134-1145.
2018
Mukherjee S, Mez J, Trittschuh EH, Saykin AJ, Gibbons LE, Fardo DW, Wessels M, Bauman J, Moore M, Choi S-E et al..  2018.  Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.. Mol Psychiatry.
2017
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MVictoria, Budde J et al..  2017.  Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.. Acta Neuropathol. 133(5):839-856.
2016
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW et al..  2016.  The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.. Neurobiol Aging. 41:115-121.
Nelson PT, Katsumata Y, Nho K, Artiushin SC, Jicha GA, Wang W-X, Abner EL, Saykin AJ, Kukull WA, Fardo DW.  2016.  Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.. Acta Neuropathol. 132(6):841-858.
2015
Mukherjee S, Walter S, Kauwe JSK, Saykin AJ, Bennett DA, Larson EB, Crane PK, M Glymour M.  2015.  Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.. Alzheimers Dement. 11(12):1439-1451.
Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM et al..  2015.  Protective variant for hippocampal atrophy identified by whole exome sequencing.. Ann Neurol. 77(3):547-52.
Wang L-S, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JDGonzalez, Cannon-Albright L, Baldwin CT, Zetterberg H et al..  2015.  Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA Neurol. 72(2):209-16.
2014
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YSon, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang L-S et al..  2014.  Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA Neurol. 71(11):1394-404.
Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, De Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A et al..  2014.  Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.. Alzheimers Dement. 10(1):45-52.
2013
Hibar DP, Stein JL, Ryles AB, Kohannim O, Jahanshad N, Medland SE, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW et al..  2013.  Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.. Brain Imaging Behav. 7(2):102-15.
2012
Ramanan VK, Shen L, Moore JH, Saykin AJ.  2012.  Pathway analysis of genomic data: concepts, methods, and prospects for future development.. Trends Genet. 28(7):323-32.
2011
Naj AC, Jun G, Beecham GW, Wang L-S, Vardarajan BNarayan, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK et al..  2011.  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.. Nat Genet. 43(5):436-41.
2010
Jun G, Naj AC, Beecham GW, Wang L-S, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, M Fallin D, Friedland R et al..  2010.  Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.. Arch Neurol. 67(12):1473-84.
Shen L, Qi Y, Kim S, Nho K, Wan J, Risacher SL, Saykin AJ.  2010.  Sparse bayesian learning for identifying imaging biomarkers in AD prediction.. Med Image Comput Comput Assist Interv. 13(Pt 3):611-8.