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Found 19 results
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De Jager, Philip L
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2021
Gao Y
,
Felsky D
,
Reyes-Dumeyer D
,
Sariya S
,
Rentería MArce
,
Ma Y
,
Klein H-U
,
Cosentino S
,
De Jager PL
,
Bennett DA
et al.
. 2021.
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
.
Alzheimers Dementia.
2020
Ouellette AR
,
Neuner SM
,
Dumitrescu L
,
Anderson LC
,
Gatti DM
,
Mahoney ER
,
Bubier JA
,
Churchill G
,
Peters L
,
Huentelman MJ
et al.
. 2020.
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
.
Cell Rep. 32(9):108091.
Reiman EM
,
Arboleda-Velasquez JF
,
Quiroz YT
,
Huentelman MJ
,
Beach TG
,
Caselli RJ
,
Chen Y
,
Su Y
,
Myers AJ
,
Hardy J
et al.
. 2020.
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
.
Nat Commun. 11(1):667.
2019
Ma Y
,
Jun GR
,
Zhang X
,
Chung J
,
Naj AC
,
Chen Y
,
Bellenguez C
,
Hamilton-Nelson K
,
Martin ER
,
Kunkle BW
et al.
. 2019.
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
.
JAMA Neurol. 76:(9):1099-1108.
Ma Y
,
Jun GR
,
Chung J
,
Zhang X
,
Kunkle BW
,
Naj AC
,
White CC
,
Bennett DA
,
De Jager PL
,
Mayeux R
et al.
. 2019.
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
.
Aging Cell. 18(4):e12964.
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Beecham G
,
Kunkle B
,
Bush WS
,
Gifford KA
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2019.
Sex differences in the genetic predictors of Alzheimer's pathology.
.
Brain. 142(9):2581-2589.
2018
Mukherjee S
,
Mez J
,
Trittschuh EH
,
Saykin AJ
,
Gibbons LE
,
Fardo DW
,
Wessels M
,
Bauman J
,
Moore M
,
Choi S-E
et al.
. 2018.
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
.
Mol Psychiatry.
Hohman TJ
,
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Beecham G
,
Kunkle B
,
Gifford KA
,
Bush WS
,
Chibnik LB
,
Mukherjee S
et al.
. 2018.
Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
.
JAMA Neurol. 75(8):989-998.
Deming Y
,
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Kunkle B
,
Gifford KA
,
Bush WS
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2018.
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
.
Acta Neuropathol. 136(6):857-872.
2017
Deming Y
,
Li Z
,
Kapoor M
,
Harari O
,
Del-Aguila JL
,
Black K
,
Carrell D
,
Cai Y
,
Fernandez MVictoria
,
Budde J
et al.
. 2017.
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
.
Acta Neuropathol. 133(5):839-856.
2016
Hohman TJ
,
Cooke-Bailey JN
,
Reitz C
,
Jun G
,
Naj A
,
Beecham GW
,
Liu Z
,
Carney RM
,
Vance JM
,
Cuccaro ML
et al.
. 2016.
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
.
Alzheimers Dement. 12(3):233-43.
2015
Ghani M
,
Reitz C
,
Cheng R
,
Vardarajan BNarayan
,
Jun G
,
Sato C
,
Naj A
,
Rajbhandary R
,
Wang L-S
,
Valladares O
et al.
. 2015.
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
.
JAMA Neurol. 72(11):1313-23.
2014
Naj AC
,
Jun G
,
Reitz C
,
Kunkle BW
,
Perry W
,
Park YSon
,
Beecham GW
,
Rajbhandary RA
,
Hamilton-Nelson KL
,
Wang L-S
et al.
. 2014.
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
.
JAMA Neurol. 71(11):1394-404.
Escott-Price V
,
Bellenguez C
,
Wang L-S
,
Choi S-H
,
Harold D
,
Jones L
,
Holmans P
,
Gerrish A
,
Vedernikov A
,
Richards A
et al.
. 2014.
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
.
PLoS One. 9(6):e94661.
Beecham GW
,
Hamilton K
,
Naj AC
,
Martin ER
,
Huentelman M
,
Myers AJ
,
Corneveaux JJ
,
Hardy J
,
Vonsattel J-P
,
Younkin SG
et al.
. 2014.
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
.
PLoS Genet. 10(9):e1004606.
Sherva R
,
Tripodis Y
,
Bennett DA
,
Chibnik LB
,
Crane PK
,
De Jager PL
,
Farrer LA
,
Saykin AJ
,
Shulman JM
,
Naj A
et al.
. 2014.
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
.
Alzheimers Dement. 10(1):45-52.
2013
Cruchaga C
,
Kauwe JSK
,
Harari O
,
Jin SChih
,
Cai Y
,
Karch CM
,
Benitez BA
,
Jeng AT
,
Skorupa T
,
Carrell D
et al.
. 2013.
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
.
Neuron. 78(2):256-68.
Reitz C
,
Jun G
,
Naj A
,
Rajbhandary R
,
Vardarajan BNarayan
,
Wang L-S
,
Valladares O
,
Lin C-F
,
Larson EB
,
Graff-Radford NR
et al.
. 2013.
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.
.
JAMA. 309(14):1483-92.
2011
Naj AC
,
Jun G
,
Beecham GW
,
Wang L-S
,
Vardarajan BNarayan
,
Buros J
,
Gallins PJ
,
Buxbaum JD
,
Jarvik GP
,
Crane PK
et al.
. 2011.
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
.
Nat Genet. 43(5):436-41.