Publications Using IGAP Summary Statistics

2019

Wang L, Qiao Y, Zhang H, Zhang Y, Hua J, Jin S, Liu G. Circulating Vitamin D Levels and Alzheimer's Disease: A Mendelian Randomization Study in the IGAP and UK Biobank. J Alzheimers Dis. 2019 Dec 2. doi: 10.3233/JAD-190713. PMID:31815694

Zhou Y, Sun X, Zhou M. Body Shape and Alzheimer's Disease: A Mendelian Randomization Analysis. Front Neurosci. 2019 Oct 10;13:1084. doi: 10.3389/fnins.2019.01084. eCollection 2019. PMID: 31649504  

Chaudhury S, Brookes KJ, Patel T, Fallows A, Guetta-Baranes T, Turton JC, Guerreiro R, Bras J, Hardy J, Francis PT, Croucher R, Holmes C, Morgan K, Thomas AJ. Alzheimer's Disease Polygenic Risk Score as a Predictor of Conversion from Mild-cognitive Impairment. Transl Psychiatry. 2019 May 24;9(1):154. doi: 10.1038/s41398-019-0485-7. Erratum in: Transl Psychiatry. 2019 Jun 11;9(1):167. PMID: 31127079

Leonenko G, Sims R, Shoai M, Frizzati A, Bossù P, Spalletta G, Fox NC, Williams J; GERAD consortium, Hardy J, Escott-Price V. Polygenic Risk and Hazard Scores for Alzheimer's Disease Prediction. Ann Clin Transl Neurol. 2019 Feb 18;6(3):456-465. doi: 10.1002/acn3.716. eCollection 2019 Mar. PMID: 30911569

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Genetic and Lifestyle Risk Factors for MRI-defined Brain Infarcts in a Population-based Setting. Neurology. 2019 Jan 16. pii: 10.1212/WNL.0000000000006851. doi: 10.1212/WNL.0000000000006851. [Epub ahead of print]. PMCID: PMC6369905. PMID: 30651383

2018

Girdhar K, Hoffman GE, Jiang Y, Brown L, Kundakovic M, Hauberg ME, Francoeur NJ, Wang Y-C, Shah H, Kavanagh DH, Zharovsky E, Jacobov R, Wiseman JR, Park R, Johnson JS, Kassim BS, Sloofman L, Mattei E, Weng Z, Sieberts SK, Peters MA, Harris BT, Lipska BK, Sklar P, Roussos P, Akbarian S. Cell-specific Histone Modification Maps in the Human Frontal Lobe Link Schizophrenia Risk to the Neuronal EpigenomeNat Neurosci. 2018 Aug;21(8):1126-1136. PMCID: PMC6063773. PMID: 30038276

Ni H, Xu M, Zhan GL, Fan Y, Zhou H, Jiang HY, Lu WH, Tan L, Zhang DF, Yao YG, Zhang C. The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer's Disease. J Alzheimers Dis. 2018 Jul 12. DOI: 10.3233/JAD-180276. PMID: 30010129

Kunutsor SK, Laukkanen JA, Burgess S. Genetically Elevated Gamma-glutamyltransferase and Alzheimer's Disease. Exp Gerontol. 2018 Jun;106:61-66. PMCID: PMC5915296. PMID: 29505811

Grace C, Clarke R, Goel A, Farrall M, Watkins H, Hopewell JC. Lack of Genetic Support for Shared Aetiology of Coronary Artery Disease and Late-onset Alzheimer's DiseaseSci Rep. 2018 May 8;8(1):7102. PMCID: PMC5940751. PMID: 29740026

Bonham LW, Karch CM, Fan CC, Tan C, Geier EG, Wang Y, Wen N, Broce IJ, Li Y, Barkovich MJ, Ferrari R, Hardy J, Momeni P, Höglinger G, Müller U, Hess CP, Sugrue LP, Dillon WP, Schellenberg GD, Miller BL, Andreassen OA, Dale AM, Barkovich AJ, Yokoyama JS, Desikan RS; International FTD-Genomics Consortium (IFGC); International Parkinson’s Disease Genetics Consortium (IPDGC); International Genomics of Alzheimer’s Project (IGAP). CXCR4 Involvement in Neurodegenerative Diseases. Transl Psychiatry. 2018 Apr 11;8(1):73. doi: 10.1038/s41398-017-0049-7. PMCID: PMC5893558. PMID: 29636460

Nordestgaard LT, Tybjærg-Hansen A, Rasmussen KL, Nordestgaard BG, Frikke-Schmidt R. Genetic Variation in Clusterin and Risk of Dementia and Ischemic Vascular Disease in the General Population: Cohort Studies and Meta-analyses of 362,338 individuals. BMC Med. 2018 Mar 14;16(1):39. PMCID: PMC5851250. PMID: 29534716

Chaudhury S, Patel T, Barber IS, Guetta-Baranes T, Brookes KJ, Chappell S, Turton J, Guerreiro R, Bras J, Hernandez D, Singleton A, Hardy J, Mann D; ARUK Consortium, Morgan K. Polygenic Risk Score in Postmortem Diagnosed Sporadic Early-onset Alzheimer's Disease. Neurobiol Aging. 2018 Feb;62:244. PMCID: PMC5995122. PMID: 29103623

Williams DM, Karlsson IK, Pedersen NL, Hägg S. Circulating Insulin-like Growth Factors and Alzheimer Disease: A Mendelian Randomization Study. Neurology. 2018 Jan 23;90(4):e291-e297. PMCID: PMC5798653. PMID: 29282328

Del-Aguila JL, Fernández MV, Schindler S, Ibanez L, Deming Y, Ma S, Saef B, Black K, Budde J, Norton J, Chasse R; Alzheimer’s Disease Neuroimaging Initiative (ADNI), Harari O, Goate A, Xiong C, Morris JC, Cruchaga C. Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline. J Alzheimers Dis. 2018;62(2):745-756. PMCID: PMC5989565. PMID: 29480181

2017

Larsson SC, Traylor M, Malik R, Dichgans M, Burgess S, Markus HS; CoSTREAM Consortium, on behalf of the International Genomics of Alzheimer’s Project. Modifiable pathways in Alzheimer's disease: Mendelian Randomization Analysis.BMJ. 2017 Dec 6;359:j5375. PMCID: PMC5717765. PMID: 29212772

Patel T, Brookes KJ, Turton J, Chaudhury S, Guetta-Baranes T, Guerreiro R, Bras J, Hernandez D, Singleton A, Francis PT, Hardy J, Morgan K. Whole-exome Sequencing of the BDR Cohort: Evidence to Support the Role of the PILRA Gene in Alzheimer's Disease. Neuropathol Appl Neurobiol. 2017 Nov 27. PMCID: PMC6005734. PMID: 29181857

McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, Levey AI, Katsel P, Haroutunian V, Schadt EE, Popko B, Casaccia P, Zhang B. Multiscale Network Modeling of Oligodendrocytes Reveals Molecular Components of Myelin Dysregulation in Alzheimer's DiseaseMol Neurodegener. 2017 Nov 6;12(1):82. PMCID: PMC5674813. PMID: 29110684

Feng YA, Cho K, Lindstrom S, Kraft P, Cormack J; IGAP Consortium, Colorectal Transdisciplinary Study (CORRECT); Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE); Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE); Transdisciplinary Research in Cancer of the Lung (TRICL), Liang L, Driver JA. Investigating the Genetic Relationship Between Alzheimer's Disease and Cancer Using GWAS Summary Statistics. Hum Genet. 2017 Oct;136(10):1341-1351. PMCID: PMC5693762. PMID: 28780673

Larsson SC, Markus HS. Branched-chain Amino Acids and Alzheimer's Disease: a Mendelian Randomization Analysis. Sci Rep. 2017 Oct 19;7(1):13604. PMCID: PMC5648806. PMID: 29051501

Wang XF, Lin X, Li DY, Zhou R, Greenbaum J, Chen YC, Zeng CP, Peng LP, Wu KH, Ao ZX, Lu JM, Guo YF, Shen J, Deng HW. Linking Alzheimer's Disease and Type 2 diabetes: Novel Shared Susceptibility Genes Detected by cFDR Approach. J Neurol Sci. 2017 Sep 15;380:262-272. PMCID: PMC6693589. PMID: 28870582

Qvist P, Christensen JH, Vardya I, Rajkumar AP, Mørk A, Paternoster V, Füchtbauer EM, Pallesen J, Fryland T, Dyrvig M, Hauberg ME, Lundsberg B, Fejgin K, Nyegaard M, Jensen K, Nyengaard JR, Mors O, Didriksen M, Børglum AD. The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice.  Biol Psychiatry. 2017 Jul 1;82(1):62-76. DOI: 10.1016/j.biopsych.2016.08.037. PMID: 27837920

Nordestgaard LT, Tybjærg-Hansen A, Nordestgaard BG, Frikke-Schmidt R. Body Mass Index and Risk of Alzheimer's Disease: A Mendelian Randomization Study of 399,536 Individuals. J Clin Endocrinol Metab. 2017 Jul 1;102(7):2310-2320. PMCID: PMC5505195. PMID: 28609829

Carrasquillo MM, Allen M, Burgess JD, Wang X, Strickland SL, Aryal S, Siuda J, Kachadoorian ML, Medway C, Younkin CS, Nair A, Wang C, Chanana P, Serie D, Nguyen T, Lincoln S, Malphrus KG, Morgan K, Golde TE, Price ND, White CC, De Jager PL, Bennett DA, Asmann YW, Crook JE, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. A Candidate Regulatory Variant at the TREM Gene Cluster Associates with Decreased Alzheimer's Disease Risk and Increased TREML1 and TREM2 Brain Gene Expression. Alzheimer's Dement. 2017 Jun;13(6):663-673. PMCID: PMC5462884. PMID: 27939925

Benn M, Nordestgaard BG, Frikke-Schmidt R, Tybjærg-Hansen A. Low LDL Cholesterol, PCSK9 and HMGCR Genetic Variation, and Risk of Alzheimer's Disease and Parkinson's Disease: Mendelian Randomization Study. BMJ. 2017 Apr 24;357:j1648. Erratum in: BMJ. 2017 Jun 29;357:j3170. PMCID: PMC5421439. PMID: 28438747

Gibson J, Russ TC, Adams MJ, Clarke TK, Howard DM, Hall LS, Fernandez-Pujals AM, Wigmore EM, Hayward C, Davies G, Murray AD, Smith BH, Porteous DJ, Deary IJ, McIntosh AM. Assessing the Presence of Shared Genetic Architecture Between Alzheimer's Disease and Major Depressive Disorder Using Genome-wide Association Data. Transl Psychiatry. 2017 Apr 18;7(4). PMCID: PMC5416691. PMID: 28418403

Karlsson IK, Ploner A, Song C, Gatz M, Pedersen NL, Hägg S. Genetic Susceptibility to Cardiovascular Disease and Risk of Dementia. Transl Psychiatry. 2017 May 30;7(5):e1142. PMCID: PMC5534941. PMID: 28556832

McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, Ophoff RA, Goris A, Bradley DG, Al-Chalabi A, van den Berg LH, Luykx JJ, Hardiman O, Veldink JH; Project MinE GWAS Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium. Genetic Correlation Between Amyotrophic Lateral Sclerosis and Schizophrenia. Nat Commun. 2017 Mar 21;8:14774. PMCID: PMC5364411. PMID: 28322246

Morgan AR, Touchard S, O'Hagan C, Sims R, Majounie E, Escott-Price V, Jones L, Williams J, Morgan BP. The Correlation Between Inflammatory Biomarkers and Polygenic Risk Score in Alzheimer's Disease.  J Alzheimers Dis. 2017;56(1):25-36. DOI: 10.3233/JAD-160889. PMID: 27911318

Myrum C, Nikolaienko O, Bramham CR, Haavik J, Zayats T. Implication of the APP Gene in Intellectual Abilities. J Alzheimers Dis. 2017;59(2):723-735. PMCID: PMC5523840. PMID: 28671113

Larsson SC, Traylor M, Burgess S, Markus HS. Genetically-Predicted Adult Height and Alzheimer's Disease.  J Alzheimers Dis. 2017;60(2):691-698. PMCID: PMC6037293. PMID: 28869480

Larsson SC, Traylor M, Burgess S, Markus HS. Genetically-Predicted Adult Height and Alzheimer's Disease.  J Alzheimers Dis. 2017;60(2):691-698. PMCID: PMC6037293. PMID: 28869480

Lacour A, Espinosa A, Louwersheimer E, Heilmann S, Hernández I, Wolfsgruber S, Fernández V, Wagner H, Rosende-Roca M, Mauleón A, Moreno-Grau S, Vargas L, Pijnenburg YA, Koene T, Rodríguez-Gómez O, Ortega G, Ruiz S, Holstege H, Sotolongo-Grau O, Kornhuber J, Peters O, Frölich L, Hüll M, Rüther E, Wiltfang J, Scherer M, Riedel-Heller S, Alegret M, Nöthen MM, Scheltens P, Wagner M, Tárraga L, Jessen F, Boada M, Maier W, van der Flier WM, Becker T, Ramirez A, Ruiz A. Genome-wide Significant Risk Factors for Alzheimer's Disease: Role in Progression to Dementia due to Alzheimer's Disease Among Subjects with Mild Cognitive Impairment. Mol Psychiatry. 2017 Jan;22(1):153-160. PMCID: PMC5414086. PMID: 26976043

2016

Mokry LE, Ross S, Morris JA, Manousaki D, Forgetta V, Richards JB. Genetically Decreased Vitamin D and Risk of Alzheimer's Disease. Neurology. 2016 Dec 13;87(24):2567-2574. PMCID: PMC5207000. PMID: 27856775

Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Pütz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Sämann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Hulshoff Pol HE, Ikeda M, Ikram MK, Jack CR Jr, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Longstreth WT Jr, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, Uitterlinden AG, Hernández MC, Van der Brug M, Van der Lugt A, Van der Wee NJ, Van Duijn CM, Van Haren NE, Van T Ent D, Van Tol MJ, Vardarajan BN, Veltman DJ, Vernooij MW, Völzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke HR, Zonderman AB, Deary IJ, DeCarli C, Schmidt H, Martin NG, De Craen AJ, Wright MJ, Launer LJ, Schumann G, Fornage M, Franke B, Debette S, Medland SE, Ikram MA, Thompson PM. Novel Genetic Loci Underlying Human Intracranial Volume Identified Through Genome-wide Association. Nat Neurosci. 2016 Dec;19(12):1569-1582. PMCID: PMC5227112.PMID: 27694991

Tosto G, Reitz C. Genomics of Alzheimer's Disease: Value of High-throughput Genomic Technologies to Dissect its Etiology. Mol Cell Probes. 2016 Dec;30(6):397-403. Epub 2016 Sep 13. Review. DOI: 10.1016/j.mcp.2016.09.001. PMID: 27618776

Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V; Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, Winsvold BS, Zwart JA, Collier DA, Desikan RS, Melle I, Werge T, Dale AM, Djurovic S, Andreassen OA. Genetic Markers of Human Evolution Are Enriched in Schizophrenia. Biol Psychiatry. 2016 Aug 15;80(4):284-292. PMCID: PMC5397584. PMID: 26681495

Mormino EC, Sperling RA, Holmes AJ, Buckner RL, De Jager PL, Smoller JW, Sabuncu MR; Alzheimer's Disease Neuroimaging Initiative. Polygenic Risk of Alzheimer's disease is Associated with Early- and Late-life Processes. Neurology. 2016 Aug 2;87(5):481-8. PMCID: PMC4970660. PMID: 27385740

Zhang DF, Fan Y, Wang D, Bi R, Zhang C, Fang Y, Yao YG. PLD3 in Alzheimer's Disease: a Modest Effect as Revealed by Updated Association and Expression Analyses. Mol Neurobiol. 2016 Aug;53(6):4034-4045. PMCID: PMC26189833. PMID: 26189833

Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF, Berr C, Amouyel P, Bennett DA, van Duijn C, DeStefano AL, Launer LJ, Ikram MA, Crane PK, Lambert JC, Mayeux R, Seshadri S; International Genomics of Alzheimer’s Project. Evaluation of a Genetic Risk Score to Improved Risk Prediction for Alzheimer's Disease. J Alzheimers Dis. 2016 Jun 18;53(3):921-32. PMCID: PMC5036102. PMID: 27340842

Pickrell JK, Berisa T, Liu JZ, Ségurel L, Tung JY, Hinds DA. Detection and Interpretation of Shared Genetic Influences on 42 Human Traits. Nat Genet. 2016 Jul;48(7):709-17. Epub 2016 May 16. Erratum in: Nat Genet. 2016 Sep 28;48(10):1296. PMCID: PMC5207801. PMID: 27182965

Fryland T, Christensen JH, Pallesen J, Mattheisen M, Palmfeldt J, Bak M, Grove J, Demontis D, Blechingberg J, Ooi HS, Nyegaard M, Hauberg ME, Tommerup N, Gregersen N, Mors O, Corydon TJ, Nielsen AL, Børglum AD. Identification of the BRD1 Interaction Network and its Impact on Mental Disorder Risk. Genome Med. 2016 May 3;8(1):53. PMCID: PMC4855718. PMID: 27142060

Lupton MK, Strike L, Hansell NK, Wen W, Mather KA, Armstrong NJ, Thalamuthu A, McMahon KL, de Zubicaray GI, Assareh AA, Simmons A, Proitsi P, Powell JF, Montgomery GW, Hibar DP, Westman E, Tsolaki M, Kloszewska I, Soininen H, Mecocci P, Velas B, Lovestone S; Alzheimer's Disease Neuroimaging Initiative, Brodaty H, Ames D, Trollor JN, Martin NG, Thompson PM, Sachdev PS, Wright MJ. The Effect of Increased Genetic Risk for Alzheimer's Disease on Hippocampal and Amygdala Volume. Neurobiol Aging. 2016 Apr;40:68-77. PMCID: PMC4883003. PMID: 26973105

Traylor M, Adib-Samii P, Harold D; Alzheimer's Disease Neuroimaging Initiative; International Stroke Genetics Consortium (ISGC), UK Young Lacunar Stroke DNA resource, Dichgans M, Williams J, Lewis CM, Markus HS; METASTROKE; International Genomics of Alzheimer's Project (IGAP), investigators. Shared Genetic Contribution to Ischaemic Stroke and Alzheimer's Disease.  Ann Neurol. 2016 Feb 23. PMCID: PMC4864940. PMID: 26913989

Walter S, Marden JR, Kubzansky LD, Mayeda ER, Crane PK, Chang SC, Cornelis M, Rehkopf DH, Mukherjee S, Glymour MM. Diabetic Phenotypes and Late-Life Dementia Risk: A Mechanism-specific Mendelian Randomization Study. Alzheimer Dis Assoc Disord. 2016 Jan-Mar;30(1):15-20. PMCID: PMC4879683. PMID: 26650880

2015

Heck A, Fastenrath M, Coynel D, Auschra B, Bickel H, Freytag V, Gschwind L, Hartmann F, Jessen F, Kaduszkiewicz H, Maier W, Milnik A, Pentzek M, Riedel-Heller SG, Spalek K, Vogler C, Wagner M, Weyerer S, Wolfsgruber S, de Quervain DJ, Papassotiropoulos A. Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease. JAMA Psychiatry. 2015 Oct;72(10):1029-36. PMCID: PMC5291164. PMID: 26332608

Allen M, Kachadoorian M, Carrasquillo MM, Karhade A, Manly L, Burgess JD, Wang C, Serie D, Wang X, Siuda J, Zou F, Chai HS, Younkin C, Crook J, Medway C, Nguyen T, Ma L, Malphrus K, Lincoln S, Petersen RC, Graff-Radford NR, Asmann YW, Dickson DW, Younkin SG, Ertekin-Taner N. Late-onset Alzheimer Disease Risk variants mark brain regulatory loci. Neurol Genet. 2015 Jul 23;1(2):e15. PMCID: PMC4807909. PMID: 27066552

2014

Hinney A, Albayrak O, Antel J, Volckmar AL, Sims R, Chapman J, Harold D, Gerrish A, Heid IM, Winkler TW, Scherag A, Wiltfang J, Williams J, Hebebrand J; GERAD Consortium; IGAP Consortium; GIANT Consortium. Genetic variation at the CELF1 (CUGBP, elav-like family member 1 gene) locus is genome-wide associated with Alzheimer's disease and obesity. Am J Med Genet B Neuropsychiatr Genet. 2014 Jun;165B(4):283-93. PMCID: PMC4879683. PMID: 24788522