ADGC Publications

Found 113 results
2018
Guerreiro R, Orme T, Naj AC, Kuzma AB, Schellenberg GD, Bras J.  2018.  Is APOE ε4 required for Alzheimer's disease to develop in TREM2 p.R47H variant carriers? Neuropathol Appl Neurobiol.
Lobach I.  2018.  Bias in parameter estimates due to omitting gene-environment interaction terms in case-control studies.. Genet Epidemiol. 42(8):838-845.
Lobach I, Sampson J, Alekseyenko A, Lobach S, Zhang L.  2018.  Case-control studies of gene-environment interactions. When a case might not be the case.. PLoS One. 13(8):e0201140.
Broce IJ, Tan CHong, Fan CChieh, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM et al..  2018.  Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.. Acta Neuropathol.
Butkiewicz M, Blue EE, Leung YYee, Jian X, Marcora E, Renton AE, Kuzma A, Wang L-S, Koboldt DC, Haines JL et al..  2018.  Functional annotation of genomic variants in studies of late-onset Alzheimer's disease.. Bioinformatics. 34(16):2724-2731.
Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C et al..  2018.  Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.. Dement Geriatr Cogn Disord. 45(1-2):1-17.
Chung J, Wang X, Maruyama T, Ma Y, Zhang X, Mez J, Sherva R, Takeyama H, Lunetta KL, Farrer LA et al..  2018.  Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages.. Alzheimers Dement. 14(5):623-633.
Chung J, Zhang X, Allen M, Wang X, Ma Y, Beecham G, Montine TJ, Younkin SG, Dickson DW, Golde TE et al..  2018.  Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease.. Alzheimers Res Ther. 10(1):22.
Teslovich TM, Kim DSeung, Yin X, Stancáková A, Jackson AU, Wielscher M, Naj A, Perry JRB, Huyghe JR, Stringham HM et al..  2018.  Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.. Hum Mol Genet. 27(9):1664-1674.
Amlie-Wolf A, Tang M, Mlynarski EE, Kuksa PP, Valladares O, Katanic Z, Tsuang D, Brown CD, Schellenberg GD, Wang L-S.  2018.  INFERNO: inferring the molecular mechanisms of noncoding genetic variants.. Nucleic Acids Res. 46(17):8740-8753.
Zhou Z, Wang W, Wang L-S, Zhang NRuonan.  2018.  Integrative DNA copy number detection and genotyping from sequencing and array-based platforms.. Bioinformatics. 34(14):2349-2355.
Gusareva ES, Twizere J-C, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K et al..  2018.  Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease.. Neurobiol Aging. 72:188.e3-188.e12.
Lancour D, Naj A, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Crovella M, Farrer LA, Kasif S.  2018.  One for all and all for One: Improving replication of genetic studies through network diffusion.. PLoS Genet. 14(4):e1007306.
Tan CHong, Fan CChieh, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM et al..  2018.  Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.. Acta Neuropathol. 135(1):85-93.
Naj AC, Lin H, Vardarajan BN, White S, Lancour D, Ma Y, Schmidt M, Sun F, Butkiewicz M, Bush WS et al..  2018.  Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.. Genomics.
Karch CM, Wen N, Fan CC, Yokoyama JS, Kouri N, Ross OA, Höglinger G, Müller U, Ferrari R, Hardy J et al..  2018.  Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.. JAMA Neurol. 75(7):860-875.
Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S et al..  2018.  Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.. JAMA Neurol. 75(8):989-998.
Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj A et al..  2018.  Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.. Ann Clin Transl Neurol. 5(4):406-417.
Raghavan NS, Brickman AM, Andrews H, Manly JJ, Schupf N, Lantigua R, Wolock CJ, Kamalakaran S, Petrovski S, Tosto G et al..  2018.  Whole-exome sequencing in 20,197 persons for rare variants in Alzheimer's disease.. Ann Clin Transl Neurol. 5(7):832-842.
2017
Beecham GW, Bis JC, Martin ER, Choi S-H, Destefano AL, van Duijn CM, Fornage M, Gabriel SB, Koboldt DC, Larson DE et al..  2017.  The Alzheimer's Disease Sequencing Project: Study design and sample selection.. Neurol Genet. 3(5):e194.
Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S et al..  2017.  Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants.. PLoS One. 12(10):e0185777.
Haddick PCG, Larson JL, Rathore N, Bhangale TR, Phung QT, Srinivasan K, Hansen DV, Lill JR, Pericak-Vance MA, Haines J et al..  2017.  A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.. J Alzheimers Dis. 56(3):1037-1054.
Kunkle BW, Vardarajan BN, Naj AC, Whitehead PL, Rolati S, Slifer S, Carney RM, Cuccaro ML, Vance JM, Gilbert JR et al..  2017.  Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.. JAMA Neurol. 74(9):1113-1122.
Cukier HN, Kunkle BK, Hamilton KL, Rolati S, Kohli MA, Whitehead PL, Jaworski J, Vance JM, Cuccaro ML, Carney RM et al..  2017.  Exome Sequencing of Extended Families with Alzheimer's Disease Identifies Novel Genes Implicated in Cell Immunity and Neuronal Function.. J Alzheimers Dis Parkinsonism. 7(4)
Steele NZR, Carr JS, Bonham LW, Geier EG, Damotte V, Miller ZA, Desikan RS, Boehme KL, Mukherjee S, Crane PK et al..  2017.  Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.. PLoS Med. 14(3):e1002272.

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