ADGC Publications

Found 42 results
Filters: Keyword is Alzheimer Disease and Author is Gerard D Schellenberg  [Clear All Filters]
2015
Wang L-S, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JDGonzalez, Cannon-Albright L, Baldwin CT, Zetterberg H et al..  2015.  Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA Neurol. 72(2):209-16.
2014
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YSon, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang L-S et al..  2014.  Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA Neurol. 71(11):1394-404.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel J-P, Younkin SG et al..  2014.  Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.. PLoS Genet. 10(9):e1004606.
Jun G, Asai H, Zeldich E, Drapeau E, Chen CD, Chung J, Park J-H, Kim S, Haroutunian V, Foroud T et al..  2014.  PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.. Ann Neurol. 76(3):379-92.
Wetzel-Smith MK, Hunkapiller J, Bhangale TR, Srinivasan K, Maloney JA, Atwal JK, Sa SM, Yaylaoglu MB, Foreman O, Ortmann W et al..  2014.  A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.. Nat Med. 20(12):1452-7.
2013
Cruchaga C, Kauwe JSK, Harari O, Jin SChih, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D et al..  2013.  GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.. Neuron. 78(2):256-68.
Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD et al..  2013.  Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).. Transl Psychiatry. 3:e256.
Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, J Gibbs R, Mayeux R, Haines JL et al..  2013.  Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.. Ann Hum Genet. 77(2):85-105.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B et al..  2013.  Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.. Nat Genet. 45(12):1452-8.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BNarayan, Wang L-S, Valladares O, Lin C-F, Larson EB, Graff-Radford NR et al..  2013.  Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.. JAMA. 309(14):1483-92.
2012
Zou F, Chai HSeng, Younkin CS, Allen M, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.. PLoS Genet. 8(6):e1002707.
Jun G, Vardarajan BN, Buros J, Yu C-E, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL et al..  2012.  Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.. Arch Neurol. 69(10):1270-9.
Coppola G, Chinnathambi S, Lee JJiYong, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R et al..  2012.  Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.. Hum Mol Genet. 21(15):3500-12.
Schellenberg GD, Montine TJ.  2012.  The genetics and neuropathology of Alzheimer's disease.. Acta Neuropathol. 124(3):305-23.
Allen M, Zou F, Chai HSeng, Younkin CS, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Novel late-onset Alzheimer disease loci variants associate with brain gene expression.. Neurology. 79(3):221-8.
2011
Naj AC, Jun G, Beecham GW, Wang L-S, Vardarajan BNarayan, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK et al..  2011.  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.. Nat Genet. 43(5):436-41.
2010
Jun G, Naj AC, Beecham GW, Wang L-S, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, M Fallin D, Friedland R et al..  2010.  Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.. Arch Neurol. 67(12):1473-84.

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