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Found 16 results
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Goate, Alison M
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2021
Kunkle BW
,
Schmidt M
,
Klein H-U
,
Naj AC
,
Hamilton-Nelson KL
,
Larson EB
,
Evans DA
,
De Jager PL
,
Crane PK
,
Buxbaum JD
et al.
. 2021.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
.
JAMA Neurol. 78(1):102-113.
2019
Baker E
,
Sims R
,
Leonenko G
,
Frizzati A
,
Harwood JC
,
Grozeva D
,
Morgan K
,
Passmore P
,
Holmes C
,
Powell J
et al.
. 2019.
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
.
PLoS One. 14(7):e0218111.
2018
Deming Y
,
Dumitrescu L
,
Barnes LL
,
Thambisetty M
,
Kunkle B
,
Gifford KA
,
Bush WS
,
Chibnik LB
,
Mukherjee S
,
De Jager PL
et al.
. 2018.
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
.
Acta Neuropathol. 136(6):857-872.
2017
Huang K-L
,
Marcora E
,
Pimenova AA
,
Di Narzo AF
,
Kapoor M
,
Jin SChih
,
Harari O
,
Bertelsen S
,
Fairfax BP
,
Czajkowski J
et al.
. 2017.
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
.
Nat Neurosci. 20(8):1052-1061.
Haddick PCG
,
Larson JL
,
Rathore N
,
Bhangale TR
,
Phung QT
,
Srinivasan K
,
Hansen DV
,
Lill JR
,
Pericak-Vance MA
,
Haines J
et al.
. 2017.
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.
.
J Alzheimers Dis. 56(3):1037-1054.
Desikan RS
,
Fan CChieh
,
Wang Y
,
Schork AJ
,
Cabral HJ
,
L Cupples A
,
Thompson WK
,
Besser L
,
Kukull WA
,
Holland D
et al.
. 2017.
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
.
PLoS Med. 14(3):e1002258.
Monsell SE
,
Mock C
,
Fardo DW
,
Bertelsen S
,
Cairns NJ
,
Roe CM
,
Ellingson SR
,
Morris JC
,
Goate AM
,
Kukull WA
. 2017.
Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.
.
Alzheimer Dis Assoc Disord. 31(3):232-238.
2016
Karch CM
,
Ezerskiy LA
,
Bertelsen S
,
Goate AM
. 2016.
Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
.
PLoS One. 11(2):e0148717.
Hohman TJ
,
Cooke-Bailey JN
,
Reitz C
,
Jun G
,
Naj A
,
Beecham GW
,
Liu Z
,
Carney RM
,
Vance JM
,
Cuccaro ML
et al.
. 2016.
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
.
Alzheimers Dement. 12(3):233-43.
2015
Barral S
,
Cheng R
,
Reitz C
,
Vardarajan B
,
Lee J
,
Kunkle B
,
Beecham G
,
Cantwell LS
,
Pericak-Vance MA
,
Farrer LA
et al.
. 2015.
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 11(12):1397-1406.
Wang L-S
,
Naj AC
,
Graham RR
,
Crane PK
,
Kunkle BW
,
Cruchaga C
,
Murcia JDGonzalez
,
Cannon-Albright L
,
Baldwin CT
,
Zetterberg H
et al.
. 2015.
Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
.
JAMA Neurol. 72(2):209-16.
2014
Naj AC
,
Jun G
,
Reitz C
,
Kunkle BW
,
Perry W
,
Park YSon
,
Beecham GW
,
Rajbhandary RA
,
Hamilton-Nelson KL
,
Wang L-S
et al.
. 2014.
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
.
JAMA Neurol. 71(11):1394-404.
Kauwe JSK
,
Bailey MH
,
Ridge PG
,
Perry R
,
Wadsworth ME
,
Hoyt KL
,
Staley LA
,
Karch CM
,
Harari O
,
Cruchaga C
et al.
. 2014.
Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
.
PLoS Genet. 10(10):e1004758.
2013
Cruchaga C
,
Kauwe JSK
,
Harari O
,
Jin SChih
,
Cai Y
,
Karch CM
,
Benitez BA
,
Jeng AT
,
Skorupa T
,
Carrell D
et al.
. 2013.
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
.
Neuron. 78(2):256-68.
2011
Naj AC
,
Jun G
,
Beecham GW
,
Wang L-S
,
Vardarajan BNarayan
,
Buros J
,
Gallins PJ
,
Buxbaum JD
,
Jarvik GP
,
Crane PK
et al.
. 2011.
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
.
Nat Genet. 43(5):436-41.
2010
Jun G
,
Naj AC
,
Beecham GW
,
Wang L-S
,
Buros J
,
Gallins PJ
,
Buxbaum JD
,
Ertekin-Taner N
,
M Fallin D
,
Friedland R
et al.
. 2010.
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
.
Arch Neurol. 67(12):1473-84.