ADGC Publications

Found 114 results
Filters: Keyword is Alzheimer Disease  [Clear All Filters]
2016
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD et al..  2016.  Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.. Neurobiol Aging. 38:141-150.
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW et al..  2016.  The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.. Neurobiol Aging. 41:115-121.
Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH et al..  2016.  Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.. Alzheimers Dement. 12(1):2-10.
Nelson PT, Katsumata Y, Nho K, Artiushin SC, Jicha GA, Wang W-X, Abner EL, Saykin AJ, Kukull WA, Fardo DW.  2016.  Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.. Acta Neuropathol. 132(6):841-858.
Tosto G, Reitz C.  2016.  Genomics of Alzheimer's disease: Value of high-throughput genomic technologies to dissect its etiology.. Mol Cell Probes. 30(6):397-403.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML et al..  2016.  Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.. Alzheimers Dement. 12(3):233-43.
Ebbert MTW, Boehme KL, Wadsworth ME, Staley LA, Mukherjee S, Crane PK, Ridge PG, Kauwe JSK.  2016.  Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk.. Alzheimers Dement. 12(2):121-129.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert J-C, Chung J, Naj AC, Kunkle BW, Wang L-S, Bis JC, Bellenguez C et al..  2016.  A novel Alzheimer disease locus located near the gene encoding tau protein.. Mol Psychiatry. 21(1):108-17.
Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL et al..  2016.  Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.. PLoS Genet. 12(10):e1006327.
2015
Ghani M, Reitz C, Cheng R, Vardarajan BNarayan, Jun G, Sato C, Naj A, Rajbhandary R, Wang L-S, Valladares O et al..  2015.  Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.. JAMA Neurol. 72(11):1313-23.
Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JRB, Boehme KL, Walter S, Kauwe JS et al..  2015.  Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.. PLoS Med. 12(6):e1001841;discussione1001841.
Escott-Price V, Sims R, Bannister C, Harold D, Vronskaya M, Majounie E, Badarinarayan N, Morgan K, Passmore P, Holmes C et al..  2015.  Common polygenic variation enhances risk prediction for Alzheimer's disease.. Brain. 138(Pt 12):3673-84.
International Genomics of Alzheimer's Disease Consortium (IGAP).  2015.  Convergent genetic and expression data implicate immunity in Alzheimer's disease.. Alzheimers Dement. 11(6):658-71.
Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen C-H, Thompson WK et al..  2015.  Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.. Mol Psychiatry. 20(12):1588-95.
Mukherjee S, Walter S, Kauwe JSK, Saykin AJ, Bennett DA, Larson EB, Crane PK, M Glymour M.  2015.  Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.. Alzheimers Dement. 11(12):1439-1451.
Malik M, Chiles J, Xi HS, Medway C, Simpson J, Potluri S, Howard D, Liang Y, Paumi CM, Mukherjee S et al..  2015.  Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.. Hum Mol Genet. 24(12):3557-70.
Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA et al..  2015.  Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.. Alzheimers Dement. 11(12):1397-1406.
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen C-H et al..  2015.  Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.. Circulation. 131(23):2061-2069.
Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM et al..  2015.  Protective variant for hippocampal atrophy identified by whole exome sequencing.. Ann Neurol. 77(3):547-52.
Wang L-S, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JDGonzalez, Cannon-Albright L, Baldwin CT, Zetterberg H et al..  2015.  Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA Neurol. 72(2):209-16.
Nelson PT, Wang W-X, Partch AB, Monsell SE, Valladares O, Ellingson SR, Wilfred BR, Naj AC, Wang L-S, Kukull WA et al..  2015.  Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.. J Neuropathol Exp Neurol. 74(1):75-84.
2014
Dysken MW, Sano M, Asthana S, Vertrees JE, Pallaki M, Llorente M, Love S, Schellenberg GD, J McCarten R, Malphurs J et al..  2014.  Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial.. JAMA. 311(1):33-44.
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YSon, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang L-S et al..  2014.  Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA Neurol. 71(11):1394-404.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel J-P, Younkin SG et al..  2014.  Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.. PLoS Genet. 10(9):e1004606.
Kauwe JSK, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C et al..  2014.  Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.. PLoS Genet. 10(10):e1004758.

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