Alzheimer's Disease
Genetics Consortium

ADGC Publications

Found 114 results

Filters: Keyword is Alzheimer Disease [Clear All Filters]

2014

Borenstein AR, Wu Y, Bowen JD, McCormick WC, Uomoto J, McCurry SM, Schellenberg GD, Larson EB. 2014. Incidence rates of dementia, Alzheimer disease, and vascular dementia in the Japanese American population in Seattle, WA: the Kame Project.. Alzheimer Dis Assoc Disord. 28(1):23-9.

Jun G, Asai H, Zeldich E, Drapeau E, Chen CD, Chung J, Park J-H, Kim S, Haroutunian V, Foroud T et al.. 2014. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.. Ann Neurol. 76(3):379-92.

Wetzel-Smith MK, Hunkapiller J, Bhangale TR, Srinivasan K, Maloney JA, Atwal JK, Sa SM, Yaylaoglu MB, Foreman O, Ortmann W et al.. 2014. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.. Nat Med. 20(12):1452-7.

Logue MW, Schu M, Vardarajan BN, Farrell J, Lunetta KL, Jun G, Baldwin CT, Deangelis MM, Farrer LA. 2014. Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways.. Neurobiol Aging. 35(6):1510.e7-18.

Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E et al.. 2014. SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.. Hum Mol Genet. 23(24):6644-58.

Logue MW, Schu M, Vardarajan BN, Farrell J, Bennett DA, Buxbaum JD, Byrd GS, Ertekin-Taner N, Evans D, Foroud T et al.. 2014. Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.. Alzheimers Dement. 10(6):609-618.e11.

Dysken MW, Guarino PD, Vertrees JE, Asthana S, Sano M, Llorente M, Pallaki M, Love S, Schellenberg GD, J McCarten R et al.. 2014. Vitamin E and memantine in Alzheimer's disease: clinical trial methods and baseline data.. Alzheimers Dement. 10(1):36-44.

2013

Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA et al.. 2013. APOE ε4 increases risk for dementia in pure synucleinopathies.. JAMA Neurol. 70(2):223-8.

Kalimo H, Lalowski M, Bogdanovic N, Philipson O, Bird TD, Nochlin D, Schellenberg GD, Brundin R, Olofsson T, Soliymani R et al.. 2013. The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ.. Acta Neuropathol Commun. 1:60.

Zhao W, Marchani EE, Cheung CYK, Steinbart EJ, Schellenberg GD, Bird TD, Wijsman EM. 2013. Genome scan in familial late-onset Alzheimer's disease: a locus on chromosome 6 contributes to age-at-onset.. Am J Med Genet B Neuropsychiatr Genet. 162B(2):201-12.

Hibar DP, Stein JL, Ryles AB, Kohannim O, Jahanshad N, Medland SE, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW et al.. 2013. Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.. Brain Imaging Behav. 7(2):102-15.

Cruchaga C, Kauwe JSK, Harari O, Jin SChih, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D et al.. 2013. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.. Neuron. 78(2):256-68.

Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD et al.. 2013. Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).. Transl Psychiatry. 3:e256.

Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, J Gibbs R, Mayeux R, Haines JL et al.. 2013. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.. Ann Hum Genet. 77(2):85-105.

Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B et al.. 2013. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.. Nat Genet. 45(12):1452-8.

Kohli MA, John-Williams K, Rajbhandary R, Naj A, Whitehead P, Hamilton K, Carney RM, Wright C, Crocco E, Gwirtzman HE et al.. 2013. Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians.. Neurobiol Aging. 34(5):1519.e5-12.

Reitz C, Mayeux R. 2013. TREM2 and neurodegenerative disease.. N Engl J Med. 369(16):1564-5.

Stutzbach LD, Xie SX, Naj AC, Albin R, Gilman S, M Y Lee V, Trojanowski JQ, Devlin B, Schellenberg GD. 2013. The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.. Acta Neuropathol Commun. 1:31.

Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BNarayan, Wang L-S, Valladares O, Lin C-F, Larson EB, Graff-Radford NR et al.. 2013. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.. JAMA. 309(14):1483-92.

2012

Zou F, Chai HSeng, Younkin CS, Allen M, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al.. 2012. Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.. PLoS Genet. 8(6):e1002707.

Jun G, Vardarajan BN, Buros J, Yu C-E, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL et al.. 2012. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.. Arch Neurol. 69(10):1270-9.

Coppola G, Chinnathambi S, Lee JJiYong, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R et al.. 2012. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.. Hum Mol Genet. 21(15):3500-12.

Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA et al.. 2012. GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.. Neurology. 79(19):1944-50.

Schellenberg GD, Montine TJ. 2012. The genetics and neuropathology of Alzheimer's disease.. Acta Neuropathol. 124(3):305-23.

Barral S, Bird T, Goate A, Farlow MR, Diaz-Arrastia R, Bennett DA, Graff-Radford N, Boeve BF, Sweet RA, Stern Y et al.. 2012. Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.. Neurology. 78(19):1464-71.

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