Alzheimer's Disease
Genetics Consortium

ADGC Publications

Found 248 results

2015

Malik M, Chiles J, Xi HS, Medway C, Simpson J, Potluri S, Howard D, Liang Y, Paumi CM, Mukherjee S et al.. 2015. Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.. Hum Mol Genet. 24(12):3557-70.

Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A, Baker M, Finch NCole A, Yoon H, Kim J et al.. 2015. Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.. Nat Commun. 6:7247.

Wheeler JM, McMillan PJ, Hawk M, Iba M, Robinson L, Xu GJ, Dombroski BA, Jeong D, Dichter MA, Juul H et al.. 2015. High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration.. Acta Neuropathol Commun. 3:33.

Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA et al.. 2015. Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.. Alzheimers Dement. 11(12):1397-1406.

Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg GD, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM et al.. 2015. PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.. Neurology. 84(10):972-80.

Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen C-H et al.. 2015. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.. Circulation. 131(23):2061-2069.

Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM et al.. 2015. Protective variant for hippocampal atrophy identified by whole exome sequencing.. Ann Neurol. 77(3):547-52.

Wang L-S, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JDGonzalez, Cannon-Albright L, Baldwin CT, Zetterberg H et al.. 2015. Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA Neurol. 72(2):209-16.

Nelson PT, Wang W-X, Partch AB, Monsell SE, Valladares O, Ellingson SR, Wilfred BR, Naj AC, Wang L-S, Kukull WA et al.. 2015. Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.. J Neuropathol Exp Neurol. 74(1):75-84.

2014

Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang W-X, Wilfred BR, Wang L-S et al.. 2014. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.. Acta Neuropathol. 127(6):825-43.

Schreiber M., Bird T.D., Tsuang D.W.. 2014. Alzheimer’s Disease Genetics. Current Behavioral Neuroscience Reports. 1(4)

Sud R, Geller ET, Schellenberg GD. 2014. Antisense-mediated Exon Skipping Decreases Tau Protein Expression: A Potential Therapy For Tauopathies.. Mol Ther Nucleic Acids. 3:e180.

Allen M, Kachadoorian M, Quicksall Z, Zou F, Chai HSeng, Younkin C, Crook JE, V Pankratz S, Carrasquillo MM, Krishnan S et al.. 2014. Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels.. Alzheimers Res Ther. 6(4):39.

Barral S, Cosentino S, Christensen K, Newman AB, Perls TT, Province MA, Mayeux R. 2014. Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly.. JAMA Neurol. 71(12):1514-9.

Dysken MW, Sano M, Asthana S, Vertrees JE, Pallaki M, Llorente M, Love S, Schellenberg GD, J McCarten R, Malphurs J et al.. 2014. Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial.. JAMA. 311(1):33-44.

Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YSon, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang L-S et al.. 2014. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA Neurol. 71(11):1394-404.

Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC et al.. 2014. Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene.. Transl Psychiatry. 4:e358.

Samocha KE, Robinson EB, Sanders SJ, Stevens C, Sabo A, McGrath LM, Kosmicki JA, Rehnström K, Mallick S, Kirby A et al.. 2014. A framework for the interpretation of de novo mutation in human disease.. Nat Genet. 46(9):944-50.

McMillan CT, Toledo JB, Avants BB, Cook PA, Wood EM, Suh ER, Irwin DJ, Powers J, Olm C, Elman L et al.. 2014. Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration.. Neurobiol Aging. 35(6):1473-82.

Barral S, Reitz C, Small SA, Mayeux R. 2014. Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals.. Neurobiol Aging. 35(12):2881.e7-2881.e10.

Escott-Price V, Bellenguez C, Wang L-S, Choi S-H, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A et al.. 2014. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.. PLoS One. 9(6):e94661.

Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel J-P, Younkin SG et al.. 2014. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.. PLoS Genet. 10(9):e1004606.

Kauwe JSK, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C et al.. 2014. Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.. PLoS Genet. 10(10):e1004758.

Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, De Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A et al.. 2014. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.. Alzheimers Dement. 10(1):45-52.

Borenstein AR, Wu Y, Bowen JD, McCormick WC, Uomoto J, McCurry SM, Schellenberg GD, Larson EB. 2014. Incidence rates of dementia, Alzheimer disease, and vascular dementia in the Japanese American population in Seattle, WA: the Kame Project.. Alzheimer Dis Assoc Disord. 28(1):23-9.

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