Publications and Presentations

(Guidelines for preparing ADGC publications)

Peer-reviewed Journal Articles

  • Zou F, Chai HS, Younkin CS, et al. "Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants." PLoS Genetics, June 2012, 8(6). (Open Access to Journal Website)
  • Allen M, Zou F, Chai HS, et al. "Novel late-onset Alzheimer's disease loci variants associate with brain gene expression."
    Neurology. 2012 Jul 17;79(3):221-8. Epub 2012 Jun 20. (Link on PubMed)
  • Naj AC, Jun G, Beecham GW, et al. "Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease." Nat Genet. 2011 May;43(5):436-41. Epub 2011 Apr 3. (PMCID: PMC3090745)
    (NIA AD Genetics Investigators 2007 - 2010 (full list in PDF format))
  • Jun G, Naj AC, Beecham GW, et al. "Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes." Arch Neurol. 2010 Dec;67(12):1473-84. Epub 2010 Aug 9. (PMCID: PMC3048805)
  • Jun G, Vardarajan BN, Buros J, et al. “Comprehensive Search for Alzheimer Disease Susceptibility Loci in the APOE Region”. Arch Neurol. 2012 Aug
    6:1-10. Epub ahead of print. Link on PubMed
  • Whitcomb DC, Larusch J, Krasinskas AM, et al. “Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and
    sporadic pancreatitis.” Nat Genet. 2012 Nov 11;44(12):1349-54. Epub 2012 Nov 11.Link on
    PubMed

Conference Abstracts

ASHG/ICHG 2011 (Montreal, Canada)

  1. Carlos Cruchaga, PhD, John S.K. Kauwe, PhD, David McKean, Matthew Bailey, David Patty, Kevin Mayo, BA, Sarah Bertelsen, MS, Anthony Hinrichs PhD, The Alzheimer’s Disease Genetic Consortium, Elaine R. Peskind, Gail Li, James B. Leverenz, Douglas Galasko, The Alzheimer’s Disease Neuroimaging Initiative, Anne M. Fagan, PhD, David M. Holtzman, MD, and Alison M. Goate, PhD.
    "Genome-wide association analyses using cerebrospinal fluid tau and phospho-tau and Aβ42 levels as endophenotypes for Alzheimer’s disease."
  2. Kara L. Hamilton, Adam C. Naj, Yo S. Park, Paul J. Gallins, Ruchita Rajbhandary, Gary W. Beecham, Eden R. Martin, Jonathan L. Haines, Margaret A. Pericak-Vance, and The Alzheimer’s Disease Genetics Consortium.
    "Genome-wide Association Analyses Identifies Novel Loci Associated with the Onset Age Among Cases with Late-Onset Alzheimer’s Disease."
  3. Gyungah Jun, Jacqueline Buros, Badri Narayan Vardarajan, Kathryn L Lunetta, Lindsay A Farrer, and The Alzheimer’s Disease Genetics Consortium.
    "Genome-wide scan suggested novel Alzheimer disease susceptibility genes by factoring influence of APOE."
  4. Adam C. Naj, Gary W. Beecham, Eden R. Martin, Paul J. Gallins, Ruchita Rajbhandary, Kara L. Hamilton, Richard Mayeux, Lindsay A. Farrer, Gerard Schellenberg, John R. Gilbert, Jonathan L. Haines, Margaret A. Pericak-Vance, and The Alzheimer’s Disease Genetics Consortium (ADGC).
    "GWAS Analysis of Autopsy Confirmed Late-Onset Alzheimer Disease Confirms Limited Effect Heterogeneity Among Known Loci."
  5. Tricia A. Thornton-Wells, Kristin D. Brown-Gentry, Eric S. Torstenson, Scott M. Dudek, Lan Jiang, Marylyn D. Ritchie, Eden R. Martin, Margaret A. Pericak-Vance, Jonathan L. Haines, The Alzheimer’s Disease Genetics Consortium.
    "Discovery and replication of gene-gene interactions in multiple independent Alzheimer Disease Genetics Consortium datasets."
  6. Badri Narayan Vardarajan, Gyungah Jun, Jacqueline Buros, The Alzheimer’s Disease Genetics Consortium, Laura Cantwell, Kathryn L Lunetta, Tatiana Foroud, Richard Mayeux, Jonathan Haines, Margaret A Pericak-Vance, Gerard Schellengberg, and Lindsay A Farrer.
    "Association of a TOMM40 Variable-length Polymorphism with Risk and Age at Onset of Alzheimer Disease is not Independent of APOE."

AAIC (ICAD) 2011, Paris, France

  1. Carlos Cruchaga, PhD, John S.K. Kauwe, PhD, Kevin Mayo, BA, Sarah Bertelsen, MS, Anthony Hinrichs, PhD, the Alzheimer Disease Genetic Consortium, Elaine Peskind, ADGC coauthors, the Alzheimer’s Disease Neuroimaging Initiative, Anne M. Fagan, PhD, David M. Holtzman, MD, and Alison M. Goate, PhD.
    "Genome-wide association analyses using cerebrospinal fluid tau and phospho-tau levels as an endophenotype for Alzheimer’s disease."
  2. Matthew Bailey, John S.K. Kauwe, PhD, Carlos Cruchaga, PhD, David McKean, Kevin Mayo, BA, Sarah Bertelsen, MS, Anthony Hinrichs, PhD, Alzheimer’s Disease Neuroimaging Initiative, ADGC coauthors, Anne M. Fagan, PhD, David M. Holtzman, MD, and Alison M. Goate, PhD.
    "Association study of recently reported AD risk variants with cerebrospinal fluid AD biomarker levels."
  3. John S.K. Kauwe, PhD ,Carlos Cruchaga, PhD, David McKean, Matthew Bailey, David Patty, Kevin Mayo, BA, Sarah Bertelsen, MS, Anthony Hinrichs, PhD, Alzheimer’s Disease Neuroimaging Initiative, ADGC coauthors, Anne M. Fagan, PhD, David M. Holtzman, MD, and Alison M. Goate, PhD.
    "Genome-wide association analyses using cerebrospinal fluid Aβ42 levels as endophenotype for Alzheimer’s disease."
  4. David Patty, John S.K. Kauwe, PhD, Carlos Cruchaga, PhD, David McKean, Matthew Bailey, Kevin Mayo, BA, Sarah Bertelsen, MS, Anthony Hinrichs, PhD, ADGC coauthors, Anne M. Fagan, PhD, David M. Holtzman, MD, and Alison M. Goate, PhD.
    "Attempt to validate recent reports of genetic associations with cerebrospinal fluid biomarkers for Alzheimer’s disease."
  5. David Peterson, John S.K. Kauwe, PhD, Jared Crowley, Chris Corcoran, Carlos Cruchaga, PhD, Alison Goate, Maria Norton, Robert C. Green MD, MPH, Ron Munger, John C.S. Breitner, Kathleen A. Welsh-Bohmer, Kostas Lyketsos, JoAnn Tschanz
    "Support for genetic association between variants in PPP3R1 and MAPT and rate of progression of Alzheimer’s disease. The Cache County Dementia Progression Study."
  6. Naj AC, Jun G, and The Alzheimer’s Disease Genetics Consortium.
    "Consortium-based Genome-wide Association Study of Late-Onset Alzheimer Disease Identifies Disease-Associated Variants in MS4A4/MS4A6E, CD2AP, CD33, and EPHA1."
  7. Martin ER, and The Alzheimer’s Disease Genetics Consortium.
    "Genome-wide Association Analyses Identifies Novel Loci Associated with the Onset Age Among Cases with Late-Onset Alzheimer’s Disease."
  8. Gyungah Jun, Jacqueline Buros, Badri Narayan Vardarajan, Kathryn Lunetta, Lindsay A Farrer, and The Alzheimer’s Disease Genetics Consortium.
    "Genome-wide scan identifies novel Alzheimer disease susceptibility genes by factoring influence of APOE."
  9. Tricia A. Thornton-Wells, Eric S. Torstenson, Scott M. Dudek, Marylyn D. Ritchie, Eden Martin, Margaret A. Pericak-Vance, Jonathan L. Haines.
    "Discovery and replication of gene-gene interactions in multiple independent Alzheimer Disease Genetics Consortium datasets."
  10. Badri Vardarajan, Gyungah Jun, Jacqueline Buros, Kathryn Lunetta, Lindsay A. Farrer, and The Alzheimer Disease Genetics Consortium.
    "Identification of gene-gene interactions for Alzheimer disease using co-operative game theory."
  11. Li-San Wang, Chiao-Feng Lin, Gerard Schellenberg, and , and The Alzheimer Disease Genetics Consortium.
    "Distribution of copy number variations in Alzheimer's Disease."
  12. Li-San Wang, Otto Valladares, Chiao-Feng Lin, Jacki Buros, Adam Naj, Lindsay Farrer, Margaret Pericak-Vance, Gerard Schellenberg, Alzheimer's Disease Genetic Consortium.
    "The ADGC Genome Browser."

Other Publications

  • David Holmes, Mind the IGAP
    The Lancet Neurology 08 April 2011(Article in Press DOI: 10.1016/S1474-4422(11)70079-5).

Conference Presentations