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Found 72 results
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Schellenberg, Gerard D
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2024
Ray NR
,
Kunkle BW
,
Hamilton-Nelson K
,
Kurup JT
,
Rajabli F
,
Qiao M
,
Vardarajan BN
,
Cosacak MI
,
Kizil C
,
Jean-Francois M
et al.
. 2024.
Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.
.
Alzheimers Dement. 20(8):5247-5261.
2023
Tejeda M
,
Farrell J
,
Zhu C
,
Wetzler L
,
Lunetta KL
,
Bush WS
,
Martin ER
,
San Wang L-
,
Schellenberg GD
,
Pericak-Vance MA
et al.
. 2023.
DNA from multiple viral species is associated with Alzheimer's disease risk.
.
Alzheimers Dement.
Ray NR
,
Ayodele T
,
Jean-Francois M
,
Baez P
,
Fernandez V
,
Bradley J
,
Crane PK
,
Dalgard CL
,
Kuzma A
,
Nicaretta H
et al.
. 2023.
The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology.
.
Alzheimers Dement.
Kang M
,
Ang TFang Alvin
,
Devine SA
,
Sherva R
,
Mukherjee S
,
Trittschuh EH
,
Gibbons LE
,
Scollard P
,
Lee M
,
Choi S-E
et al.
. 2023.
A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.
.
Mol Neurodegener. 18(1):40.
Li D
,
Farrell JJ
,
Mez J
,
Martin ER
,
Bush WS
,
Ruiz A
,
Boada M
,
de Rojas I
,
Mayeux R
,
Haines JL
et al.
. 2023.
Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.
.
Alzheimers Dement.
2022
Rajabli F
,
Tosto G
,
Hamilton-Nelson KL
,
Kunkle BW
,
Vardarajan BN
,
Naj A
,
Whitehead PG
,
Gardner OK
,
Bush WS
,
Sariya S
et al.
. 2022.
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.
.
Alzheimers Dement.
Kuksa PP
,
Liu C-L
,
Fu W
,
Qu L
,
Zhao Y
,
Katanic Z
,
Clark K
,
Kuzma AB
,
Ho P-C
,
Tzeng K-T
et al.
. 2022.
Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.
.
J Alzheimers Dis. 86(1):461-477.
Hopfner F
,
Tietz AK
,
Ruf VC
,
Ross OA
,
Koga S
,
Dickson D
,
Aguzzi A
,
Attems J
,
Beach T
,
Beller A
et al.
. 2022.
Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.
.
Mov Disord. 37(10):2110-2121.
Holstege H
,
Hulsman M
,
Charbonnier C
,
Grenier-Boley B
,
Quenez O
,
Grozeva D
,
van Rooij JGJ
,
Sims R
,
Ahmad S
,
Amin N
et al.
. 2022.
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.
.
Nat Genet. 54(12):1786-1794.
Chung J
,
Das A
,
Sun X
,
Sobreira DR
,
Leung YYee
,
Igartua C
,
Mozaffari S
,
Chou Y-F
,
Thiagalingam S
,
Mez J
et al.
. 2022.
Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.
.
Alzheimers Dement.
Shade LMp
,
Katsumata Y
,
Hohman TJ
,
Nho K
,
Saykin AJ
,
Mukherjee S
,
Boehme KL
,
Kauwe JSk
,
Farrer LA
,
Schellenberg GD
et al.
. 2022.
Genome-wide association study of brain arteriolosclerosis.
.
J Cereb Blood Flow Metab. 42(8):1437-1450.
Rajabli F
,
Beecham GW
,
Hendrie HC
,
Baiyewu O
,
Ogunniyi A
,
Gao S
,
Kushch NA
,
Lipkin-Vasquez M
,
Hamilton-Nelson KL
,
Young JI
et al.
. 2022.
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.
.
PLoS Genet. 18(7):e1009977.
Jun GR
,
You Y
,
Zhu C
,
Meng G
,
Chung J
,
Panitch R
,
Hu J
,
Xia W
,
Bennett DA
,
Foroud TM
et al.
. 2022.
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.
.
Alzheimers Dement. 18(11):2042-2054.
Eissman JM
,
Dumitrescu L
,
Mahoney ER
,
Smith AN
,
Mukherjee S
,
Lee ML
,
Scollard P
,
Choi SEun
,
Bush WS
,
Engelman CD
et al.
. 2022.
Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
.
Brain. 145(7):2541-2554.
2021
Zhang X
,
Farrell JJ
,
Tong T
,
Hu J
,
Zhu C
,
San Wang L-
,
Mayeux R
,
Haines JL
,
Pericak-Vance MA
,
Schellenberg GD
et al.
. 2021.
Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease.
.
Alzheimers Dement.
Gao Y
,
Felsky D
,
Reyes-Dumeyer D
,
Sariya S
,
Rentería MArce
,
Ma Y
,
Klein H-U
,
Cosentino S
,
De Jager PL
,
Bennett DA
et al.
. 2021.
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
.
Alzheimers Dementia.
Kunkle BW
,
Schmidt M
,
Klein H-U
,
Naj AC
,
Hamilton-Nelson KL
,
Larson EB
,
Evans DA
,
De Jager PL
,
Crane PK
,
Buxbaum JD
et al.
. 2021.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
.
JAMA Neurol. 78(1):102-113.
2020
Reiman EM
,
Arboleda-Velasquez JF
,
Quiroz YT
,
Huentelman MJ
,
Beach TG
,
Caselli RJ
,
Chen Y
,
Su Y
,
Myers AJ
,
Hardy J
et al.
. 2020.
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
.
Nat Commun. 11(1):667.
2019
Wheeler JM
,
McMillan P
,
Strovas TJ
,
Liachko NF
,
Amlie-Wolf A
,
Kow RL
,
Klein RL
,
Szot P
,
Robinson L
,
Guthrie C
et al.
. 2019.
Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.
.
Sci Transl Med. 11(523)
Ma Y
,
Jun GR
,
Zhang X
,
Chung J
,
Naj AC
,
Chen Y
,
Bellenguez C
,
Hamilton-Nelson K
,
Martin ER
,
Kunkle BW
et al.
. 2019.
Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
.
JAMA Neurol. 76:(9):1099-1108.
Cali CP
,
Patino M
,
Tai YKit
,
Ho WYun
,
McLean CA
,
Morris CM
,
Seeley WW
,
Miller BL
,
Gaig C
,
Vonsattel JPaul G
et al.
. 2019.
C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.
.
Acta Neuropathol. 138(5):795-811.
Bis JC
,
Jian X
,
Kunkle BW
,
Chen Y
,
Hamilton-Nelson KL
,
Bush WS
,
Salerno WJ
,
Lancour D
,
Ma Y
,
Renton AE
et al.
. 2019.
Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
.
Mol Psychiatry.
Ma Y
,
Jun GR
,
Chung J
,
Zhang X
,
Kunkle BW
,
Naj AC
,
White CC
,
Bennett DA
,
De Jager PL
,
Mayeux R
et al.
. 2019.
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
.
Aging Cell. 18(4):e12964.
Baker E
,
Sims R
,
Leonenko G
,
Frizzati A
,
Harwood JC
,
Grozeva D
,
Morgan K
,
Passmore P
,
Holmes C
,
Powell J
et al.
. 2019.
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
.
PLoS One. 14(7):e0218111.
Amlie-Wolf A
,
Tang M
,
Way J
,
Dombroski B
,
Jiang M
,
Vrettos N
,
Chou Y-F
,
Zhao Y
,
Kuzma A
,
Mlynarski EE
et al.
. 2019.
Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants.
.
J Alzheimers Dis. 72(1):301-318.
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