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Found 27 results
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Gerard D Schellenberg
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2018
Blue EE
,
Bis JC
,
Dorschner MO
,
Tsuang DW
,
Barral SM
,
Beecham G
,
Below JE
,
Bush WS
,
Butkiewicz M
,
Cruchaga C
et al.
. 2018.
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
.
Dement Geriatr Cogn Disord. 45(1-2):1-17.
2017
Haddick PCG
,
Larson JL
,
Rathore N
,
Bhangale TR
,
Phung QT
,
Srinivasan K
,
Hansen DV
,
Lill JR
,
Pericak-Vance MA
,
Haines J
et al.
. 2017.
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.
.
J Alzheimers Dis. 56(3):1037-1054.
Kunkle BW
,
Vardarajan BN
,
Naj AC
,
Whitehead PL
,
Rolati S
,
Slifer S
,
Carney RM
,
Cuccaro ML
,
Vance JM
,
Gilbert JR
et al.
. 2017.
Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.
.
JAMA Neurol. 74(9):1113-1122.
Desikan RS
,
Fan CChieh
,
Wang Y
,
Schork AJ
,
Cabral HJ
,
L Cupples A
,
Thompson WK
,
Besser L
,
Kukull WA
,
Holland D
et al.
. 2017.
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
.
PLoS Med. 14(3):e1002258.
Tan CHong
,
Hyman BT
,
Tan JJX
,
Hess CP
,
Dillon WP
,
Schellenberg GD
,
Besser LM
,
Kukull WA
,
Kauppi K
,
McEvoy LK
et al.
. 2017.
Polygenic hazard scores in preclinical Alzheimer disease.
.
Ann Neurol. 82(3):484-488.
Mez J
,
Chung J
,
Jun G
,
Kriegel J
,
Bourlas AP
,
Sherva R
,
Logue MW
,
Barnes LL
,
Bennett DA
,
Buxbaum JD
et al.
. 2017.
Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
.
Alzheimers Dement. 13(2):119-129.
2016
Ridge PG
,
Hoyt KB
,
Boehme K
,
Mukherjee S
,
Crane PK
,
Haines JL
,
Mayeux R
,
Farrer LA
,
Pericak-Vance MA
,
Schellenberg GD
et al.
. 2016.
Assessment of the genetic variance of late-onset Alzheimer's disease.
.
Neurobiol Aging. 41:200.e13-200.e20.
Yokoyama JS
,
Wang Y
,
Schork AJ
,
Thompson WK
,
Karch CM
,
Cruchaga C
,
McEvoy LK
,
Witoelar A
,
Chen C-H
,
Holland D
et al.
. 2016.
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.
.
JAMA Neurol. 73(6):691-7.
Hohman TJ
,
Bush WS
,
Jiang L
,
Brown-Gentry KD
,
Torstenson ES
,
Dudek SM
,
Mukherjee S
,
Naj A
,
Kunkle BW
,
Ritchie MD
et al.
. 2016.
Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.
.
Neurobiol Aging. 38:141-150.
Hohman TJ
,
Cooke-Bailey JN
,
Reitz C
,
Jun G
,
Naj A
,
Beecham GW
,
Liu Z
,
Carney RM
,
Vance JM
,
Cuccaro ML
et al.
. 2016.
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
.
Alzheimers Dement. 12(3):233-43.
Jakobsdottir J
,
van der Lee SJ
,
Bis JC
,
Chouraki V
,
Li-Kroeger D
,
Yamamoto S
,
Grove ML
,
Naj A
,
Vronskaya M
,
Salazar JL
et al.
. 2016.
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.
.
PLoS Genet. 12(10):e1006327.
2015
Desikan RS
,
Schork AJ
,
Wang Y
,
Witoelar A
,
Sharma M
,
McEvoy LK
,
Holland D
,
Brewer JB
,
Chen C-H
,
Thompson WK
et al.
. 2015.
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.
.
Mol Psychiatry. 20(12):1588-95.
Barral S
,
Cheng R
,
Reitz C
,
Vardarajan B
,
Lee J
,
Kunkle B
,
Beecham G
,
Cantwell LS
,
Pericak-Vance MA
,
Farrer LA
et al.
. 2015.
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 11(12):1397-1406.
Beecham GW
,
Dickson DW
,
Scott WK
,
Martin ER
,
Schellenberg GD
,
Nuytemans K
,
Larson EB
,
Buxbaum JD
,
Trojanowski JQ
,
Van Deerlin VM
et al.
. 2015.
PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.
.
Neurology. 84(10):972-80.
Desikan RS
,
Schork AJ
,
Wang Y
,
Thompson WK
,
Dehghan A
,
Ridker PM
,
Chasman DI
,
McEvoy LK
,
Holland D
,
Chen C-H
et al.
. 2015.
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.
.
Circulation. 131(23):2061-2069.
Wang L-S
,
Naj AC
,
Graham RR
,
Crane PK
,
Kunkle BW
,
Cruchaga C
,
Murcia JDGonzalez
,
Cannon-Albright L
,
Baldwin CT
,
Zetterberg H
et al.
. 2015.
Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
.
JAMA Neurol. 72(2):209-16.
2014
Naj AC
,
Jun G
,
Reitz C
,
Kunkle BW
,
Perry W
,
Park YSon
,
Beecham GW
,
Rajbhandary RA
,
Hamilton-Nelson KL
,
Wang L-S
et al.
. 2014.
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
.
JAMA Neurol. 71(11):1394-404.
Jun G
,
Asai H
,
Zeldich E
,
Drapeau E
,
Chen CD
,
Chung J
,
Park J-H
,
Kim S
,
Haroutunian V
,
Foroud T
et al.
. 2014.
PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
.
Ann Neurol. 76(3):379-92.
Wetzel-Smith MK
,
Hunkapiller J
,
Bhangale TR
,
Srinivasan K
,
Maloney JA
,
Atwal JK
,
Sa SM
,
Yaylaoglu MB
,
Foreman O
,
Ortmann W
et al.
. 2014.
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
.
Nat Med. 20(12):1452-7.
2013
Cruchaga C
,
Kauwe JSK
,
Harari O
,
Jin SChih
,
Cai Y
,
Karch CM
,
Benitez BA
,
Jeng AT
,
Skorupa T
,
Carrell D
et al.
. 2013.
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
.
Neuron. 78(2):256-68.
Holton P
,
Ryten M
,
Nalls M
,
Trabzuni D
,
Weale ME
,
Hernandez D
,
Crehan H
,
J Gibbs R
,
Mayeux R
,
Haines JL
et al.
. 2013.
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
.
Ann Hum Genet. 77(2):85-105.
Lambert JC
,
Ibrahim-Verbaas CA
,
Harold D
,
Naj AC
,
Sims R
,
Bellenguez C
,
DeStafano AL
,
Bis JC
,
Beecham GW
,
Grenier-Boley B
et al.
. 2013.
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
.
Nat Genet. 45(12):1452-8.
2012
Whitcomb DC
,
LaRusch J
,
Krasinskas AM
,
Klei L
,
Smith JP
,
Brand RE
,
Neoptolemos JP
,
Lerch MM
,
Tector M
,
Sandhu BS
et al.
. 2012.
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
.
Nat Genet. 44(12):1349-54.
Jun G
,
Vardarajan BN
,
Buros J
,
Yu C-E
,
Hawk MV
,
Dombroski BA
,
Crane PK
,
Larson EB
,
Mayeux R
,
Haines JL
et al.
. 2012.
Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.
.
Arch Neurol. 69(10):1270-9.
Allen M
,
Zou F
,
Chai HSeng
,
Younkin CS
,
Crook J
,
V Pankratz S
,
Carrasquillo MM
,
Rowley CN
,
Nair AA
,
Middha S
et al.
. 2012.
Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
.
Neurology. 79(3):221-8.
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