ADGC Publications

Found 75 results
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2017
Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S et al..  2017.  Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants.. PLoS One. 12(10):e0185777.
Haddick PCG, Larson JL, Rathore N, Bhangale TR, Phung QT, Srinivasan K, Hansen DV, Lill JR, Pericak-Vance MA, Haines J et al..  2017.  A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.. J Alzheimers Dis. 56(3):1037-1054.
Kunkle BW, Vardarajan BN, Naj AC, Whitehead PL, Rolati S, Slifer S, Carney RM, Cuccaro ML, Vance JM, Gilbert JR et al..  2017.  Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.. JAMA Neurol. 74(9):1113-1122.
Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB, Momeni P et al..  2017.  Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.. J Neurol Neurosurg Psychiatry. 88(2):152-164.
Desikan RS, Fan CChieh, Wang Y, Schork AJ, Cabral HJ, L Cupples A, Thompson WK, Besser L, Kukull WA, Holland D et al..  2017.  Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.. PLoS Med. 14(3):e1002258.
Monsell SE, Mock C, Fardo DW, Bertelsen S, Cairns NJ, Roe CM, Ellingson SR, Morris JC, Goate AM, Kukull WA.  2017.  Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.. Alzheimer Dis Assoc Disord. 31(3):232-238.
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MVictoria, Budde J et al..  2017.  Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.. Acta Neuropathol. 133(5):839-856.
Chapuis J, Flaig A, Grenier-Boley B, Eysert F, Pottiez V, Deloison G, Vandeputte A, Ayral A-M, Mendes T, Desai S et al..  2017.  Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.. Acta Neuropathol. 133(6):955-966.
Naj AC, Schellenberg GD.  2017.  Genomic variants, genes, and pathways of Alzheimer's disease: An overview.. Am J Med Genet B Neuropsychiatr Genet. 174(1):5-26.
Butkiewicz M, Haines JL, Bush WS.  2017.  Introducing COCOS: codon consequence scanner for annotating reading frame changes induced by stop-lost and frame shift variants.. Bioinformatics. 33(10):1561-1562.
Tan CHong, Hyman BT, Tan JJX, Hess CP, Dillon WP, Schellenberg GD, Besser LM, Kukull WA, Kauppi K, McEvoy LK et al..  2017.  Polygenic hazard scores in preclinical Alzheimer disease.. Ann Neurol. 82(3):484-488.
Ighodaro ET, Abner EL, Fardo DW, Lin A-L, Katsumata Y, Schmitt FA, Kryscio RJ, Jicha GA, Neltner JH, Monsell SE et al..  2017.  Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals.. J Cereb Blood Flow Metab. 37(1):201-216.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK et al..  2017.  Transethnic genome-wide scan identifies novel Alzheimer's disease loci.. Alzheimers Dement. 13(7):727-738.
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD et al..  2017.  Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.. Alzheimers Dement. 13(2):119-129.
2016
Karch CM, Ezerskiy LA, Bertelsen S, Goate AM.  2016.  Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.. PLoS One. 11(2):e0148717.
Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD et al..  2016.  Assessment of the genetic variance of late-onset Alzheimer's disease.. Neurobiol Aging. 41:200.e13-200.e20.
Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen C-H, Holland D et al..  2016.  Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.. JAMA Neurol. 73(6):691-7.
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD et al..  2016.  Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.. Neurobiol Aging. 38:141-150.
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW et al..  2016.  The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.. Neurobiol Aging. 41:115-121.
Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH et al..  2016.  Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.. Alzheimers Dement. 12(1):2-10.
Nelson PT, Katsumata Y, Nho K, Artiushin SC, Jicha GA, Wang W-X, Abner EL, Saykin AJ, Kukull WA, Fardo DW.  2016.  Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.. Acta Neuropathol. 132(6):841-858.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML et al..  2016.  Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.. Alzheimers Dement. 12(3):233-43.
Ebbert MTW, Boehme KL, Wadsworth ME, Staley LA, Mukherjee S, Crane PK, Ridge PG, Kauwe JSK.  2016.  Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk.. Alzheimers Dement. 12(2):121-129.

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