ADGC Publications

Found 47 results
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2017
Haddick PCG, Larson JL, Rathore N, Bhangale TR, Phung QT, Srinivasan K, Hansen DV, Lill JR, Pericak-Vance MA, Haines J et al..  2017.  A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.. J Alzheimers Dis. 56(3):1037-1054.
Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB, Momeni P et al..  2017.  Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.. J Neurol Neurosurg Psychiatry. 88(2):152-164.
Desikan RS, Fan CChieh, Wang Y, Schork AJ, Cabral HJ, L Cupples A, Thompson WK, Besser L, Kukull WA, Holland D et al..  2017.  Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.. PLoS Med. 14(3):e1002258.
Monsell SE, Mock C, Fardo DW, Bertelsen S, Cairns NJ, Roe CM, Ellingson SR, Morris JC, Goate AM, Kukull WA.  2017.  Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.. Alzheimer Dis Assoc Disord. 31(3):232-238.
Naj AC, Schellenberg GD.  2017.  Genomic variants, genes, and pathways of Alzheimer's disease: An overview.. Am J Med Genet B Neuropsychiatr Genet. 174(1):5-26.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK et al..  2017.  Transethnic genome-wide scan identifies novel Alzheimer's disease loci.. Alzheimers Dement. 13(7):727-738.
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD et al..  2017.  Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.. Alzheimers Dement. 13(2):119-129.
2016
Karch CM, Ezerskiy LA, Bertelsen S, Goate AM.  2016.  Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.. PLoS One. 11(2):e0148717.
Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD et al..  2016.  Assessment of the genetic variance of late-onset Alzheimer's disease.. Neurobiol Aging. 41:200.e13-200.e20.
Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen C-H, Holland D et al..  2016.  Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.. JAMA Neurol. 73(6):691-7.
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD et al..  2016.  Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.. Neurobiol Aging. 38:141-150.
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW et al..  2016.  The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.. Neurobiol Aging. 41:115-121.
Nelson PT, Katsumata Y, Nho K, Artiushin SC, Jicha GA, Wang W-X, Abner EL, Saykin AJ, Kukull WA, Fardo DW.  2016.  Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.. Acta Neuropathol. 132(6):841-858.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML et al..  2016.  Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.. Alzheimers Dement. 12(3):233-43.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert J-C, Chung J, Naj AC, Kunkle BW, Wang L-S, Bis JC, Bellenguez C et al..  2016.  A novel Alzheimer disease locus located near the gene encoding tau protein.. Mol Psychiatry. 21(1):108-17.
2015
Ghani M, Reitz C, Cheng R, Vardarajan BNarayan, Jun G, Sato C, Naj A, Rajbhandary R, Wang L-S, Valladares O et al..  2015.  Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.. JAMA Neurol. 72(11):1313-23.
Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JRB, Boehme KL, Walter S, Kauwe JS et al..  2015.  Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.. PLoS Med. 12(6):e1001841;discussione1001841.
International Genomics of Alzheimer's Disease Consortium (IGAP).  2015.  Convergent genetic and expression data implicate immunity in Alzheimer's disease.. Alzheimers Dement. 11(6):658-71.
Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen C-H, Thompson WK et al..  2015.  Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus.. Mol Psychiatry. 20(12):1588-95.
Mukherjee S, Walter S, Kauwe JSK, Saykin AJ, Bennett DA, Larson EB, Crane PK, M Glymour M.  2015.  Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.. Alzheimers Dement. 11(12):1439-1451.
Malik M, Chiles J, Xi HS, Medway C, Simpson J, Potluri S, Howard D, Liang Y, Paumi CM, Mukherjee S et al..  2015.  Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.. Hum Mol Genet. 24(12):3557-70.
Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA et al..  2015.  Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease.. Alzheimers Dement. 11(12):1397-1406.
Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg GD, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM et al..  2015.  PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.. Neurology. 84(10):972-80.
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen C-H et al..  2015.  Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.. Circulation. 131(23):2061-2069.

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