ADGC Publications

Found 248 results
2020
Miller JB, Ward E, Staley LA, Stevens J, Teerlink CC, Tavana JP, Cloward M, Page M, Dayton L, Cannon-Albright LA et al..  2020.  Identification and genomic analysis of pedigrees with exceptional longevity identifies candidate rare variants.. Neurobiol Dis. 143:104972.
Ajnakina O, Cadar D, Steptoe A.  2020.  Interplay between Socioeconomic Markers and Polygenic Predisposition on Timing of Dementia Diagnosis.. J Am Geriatr Soc. 68(7):1529-1536.
Strickland SL, Reddy JS, Allen M, N'songo A, Burgess JD, Corda MM, Ballard T, Wang X, Carrasquillo MM, Biernacka JM et al..  2020.  MAPT haplotype-stratified GWAS reveals differential association for AD risk variants.. Alzheimers Dement.
2019
Wheeler JM, McMillan P, Strovas TJ, Liachko NF, Amlie-Wolf A, Kow RL, Klein RL, Szot P, Robinson L, Guthrie C et al..  2019.  Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.. Sci Transl Med. 11(523)
Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW et al..  2019.  Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.. JAMA Neurol. 76:(9):1099-1108.
Patel D, Mez J, Vardarajan BN, Staley L, Chung J, Zhang X, Farrell JJ, Rynkiewicz MJ, Cannon-Albright LA, Teerlink CC et al..  2019.  Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.. JAMA Netw Open. 2(3):e191350.
Tosto G, Vardarajan B, Sariya S, Brickman AM, Andrews H, Manly JJ, Schupf N, Reyes-Dumeyer D, Lantigua R, Bennett DA et al..  2019.  Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease.. JAMA Neurol. 76:(8):942-948.
Cali CP, Patino M, Tai YKit, Ho WYun, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPaul G et al..  2019.  C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy.. Acta Neuropathol. 138(5):795-811.
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE et al..  2019.  Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Mol Psychiatry.
Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R et al..  2019.  CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.. Aging Cell. 18(4):e12964.
Broce IJ, Tan CHong, Fan CChieh, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM et al..  2019.  Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.. Acta Neuropathol. 137:137(2):209-226.
Baker E, Sims R, Leonenko G, Frizzati A, Harwood JC, Grozeva D, Morgan K, Passmore P, Holmes C, Powell J et al..  2019.  Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.. PLoS One. 14(7):e0218111.
Lo M-T, Kauppi K, Fan C-C, Sanyal N, Reas ET, Sundar VS, Lee W-C, Desikan RS, McEvoy LK, Chen C-H.  2019.  Identification of genetic heterogeneity of Alzheimer's disease across age. Neurobiol Aging. 84:243.e1-243.e9.
Amlie-Wolf A, Tang M, Way J, Dombroski B, Jiang M, Vrettos N, Chou Y-F, Zhao Y, Kuzma A, Mlynarski EE et al..  2019.  Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants.. J Alzheimers Dis. 72(1):301-318.
Tan CHong, Bonham LW, Fan CChieh, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL et al..  2019.  Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.. Brain. 142(2):460-470.
Choi KYeong, Lee JJae, Gunasekaran TIniyan, Kang S, Lee W, Jeong J, Lim HJae, Zhang X, Zhu C, Won S-Y et al..  2019.  Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of ε4 on Alzheimer's Disease Risk in a Multiracial Sample.. J Clin Med. 8(8)
Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JL et al..  2019.  A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.. Alzheimers Dement. 15(3):441-452.
Sariya S, Lee JH, Mayeux R, Vardarajan BN, Reyes-Dumeyer D, Manly JJ, Brickman AM, Lantigua R, Medrano M, Jimenez-Velazquez IZ et al..  2019.  Rare Variants Imputation in Admixed Populations: Comparison Across Reference Panels and Bioinformatics Tools.. Front Genet. 10:239.
Gardner OK, Wang L, Van Booven D, Whitehead PL, Hamilton-Nelson KL, Adams LD, Starks TD, Hofmann NK, Vance JM, Cuccaro ML et al..  2019.  RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways.. Hum Mol Genet. 28(18):3053-3061.
Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Bush WS, Gifford KA, Chibnik LB, Mukherjee S, De Jager PL et al..  2019.  Sex differences in the genetic predictors of Alzheimer's pathology.. Brain. 142(9):2581-2589.
Lobach I, Kim I, Alekseyenko A, Lobach S, Zhang L.  2019.  A Simple Approximation to Bias in Gene-Environment Interaction Estimates When a Case Might Not Be the Case. Front Genet. 10:886.
Hu Y, Li M, Lu Q, Weng H, Wang J, Zekavat SM, Yu Z, Li B, Gu J, Muchnik S et al..  2019.  A Statistical Framework for Cross-tissue Transcriptome-wide Association Analysis.. Nat Genet. 51(3):568-576.
Katsumata Y, Nelson PT, Estus S, Fardo DW.  2019.  Translating Alzheimer's Disease-associated Polymorphisms into Functional Candidates: a Survey of IGAP Genes and SNPs.. Neurobiol Aging. 74:135-146.
Leung YYee, Valladares O, Chou Y-F, Lin H-J, Kuzma AB, Cantwell L, Qu L, Gangadharan P, Salerno WJ, Schellenberg GD et al..  2019.  VCPA: genomic variant calling pipeline and data management tool for Alzheimer's Disease Sequencing Project.. Bioinformatics. 35(11):1985.
2018
Nafikov RA, Nato AQ, Sohi H, Wang B, Brown L, Horimoto AR, Vardarajan BN, Barral SM, Tosto G, Mayeux RP et al..  2018.  Analysis of Pedigree Data in Populations with Multiple Ancestries: Strategies for Dealing with Admixture in Caribbean Hispanic Families from the ADSP.. Genet Epidemiol. 42(6):500-515.

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