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Found 23 results
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Kukull, Walter A
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Alzheimer Disease
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2023
Kang M
,
Ang TFang Alvin
,
Devine SA
,
Sherva R
,
Mukherjee S
,
Trittschuh EH
,
Gibbons LE
,
Scollard P
,
Lee M
,
Choi S-E
et al.
. 2023.
A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.
.
Mol Neurodegener. 18(1):40.
2022
Katsumata Y
,
Shade LM
,
Hohman TJ
,
Schneider JA
,
Bennett DA
,
Farfel JM
,
Kukull WA
,
Fardo DW
,
Nelson PT
. 2022.
Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.
.
Neurobiol Dis. 174:105880.
2021
Kunkle BW
,
Schmidt M
,
Klein H-U
,
Naj AC
,
Hamilton-Nelson KL
,
Larson EB
,
Evans DA
,
De Jager PL
,
Crane PK
,
Buxbaum JD
et al.
. 2021.
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
.
JAMA Neurol. 78(1):102-113.
2019
Tan CHong
,
Bonham LW
,
Fan CChieh
,
Mormino EC
,
Sugrue LP
,
Broce IJ
,
Hess CP
,
Yokoyama JS
,
Rabinovici GD
,
Miller BL
et al.
. 2019.
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
.
Brain. 142(2):460-470.
2018
Lee S
,
Zhou X
,
Gao Y
,
Vardarajan B
,
Reyes-Dumeyer D
,
Rajan KB
,
Wilson RS
,
Evans DA
,
Besser LM
,
Kukull WA
et al.
. 2018.
Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly.
.
PLoS One. 13(11):e0206803.
2017
Desikan RS
,
Fan CChieh
,
Wang Y
,
Schork AJ
,
Cabral HJ
,
L Cupples A
,
Thompson WK
,
Besser L
,
Kukull WA
,
Holland D
et al.
. 2017.
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
.
PLoS Med. 14(3):e1002258.
Monsell SE
,
Mock C
,
Fardo DW
,
Bertelsen S
,
Cairns NJ
,
Roe CM
,
Ellingson SR
,
Morris JC
,
Goate AM
,
Kukull WA
. 2017.
Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.
.
Alzheimer Dis Assoc Disord. 31(3):232-238.
Tan CHong
,
Hyman BT
,
Tan JJX
,
Hess CP
,
Dillon WP
,
Schellenberg GD
,
Besser LM
,
Kukull WA
,
Kauppi K
,
McEvoy LK
et al.
. 2017.
Polygenic hazard scores in preclinical Alzheimer disease.
.
Ann Neurol. 82(3):484-488.
Jun GR
,
Chung J
,
Mez J
,
Barber R
,
Beecham GW
,
Bennett DA
,
Buxbaum JD
,
Byrd GS
,
Carrasquillo MM
,
Crane PK
et al.
. 2017.
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
.
Alzheimers Dement. 13(7):727-738.
Mez J
,
Chung J
,
Jun G
,
Kriegel J
,
Bourlas AP
,
Sherva R
,
Logue MW
,
Barnes LL
,
Bennett DA
,
Buxbaum JD
et al.
. 2017.
Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
.
Alzheimers Dement. 13(2):119-129.
2016
Nelson PT
,
Katsumata Y
,
Nho K
,
Artiushin SC
,
Jicha GA
,
Wang W-X
,
Abner EL
,
Saykin AJ
,
Kukull WA
,
Fardo DW
. 2016.
Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging.
.
Acta Neuropathol. 132(6):841-858.
Hohman TJ
,
Cooke-Bailey JN
,
Reitz C
,
Jun G
,
Naj A
,
Beecham GW
,
Liu Z
,
Carney RM
,
Vance JM
,
Cuccaro ML
et al.
. 2016.
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
.
Alzheimers Dement. 12(3):233-43.
2015
Ghani M
,
Reitz C
,
Cheng R
,
Vardarajan BNarayan
,
Jun G
,
Sato C
,
Naj A
,
Rajbhandary R
,
Wang L-S
,
Valladares O
et al.
. 2015.
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
.
JAMA Neurol. 72(11):1313-23.
Wang L-S
,
Naj AC
,
Graham RR
,
Crane PK
,
Kunkle BW
,
Cruchaga C
,
Murcia JDGonzalez
,
Cannon-Albright L
,
Baldwin CT
,
Zetterberg H
et al.
. 2015.
Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
.
JAMA Neurol. 72(2):209-16.
Nelson PT
,
Wang W-X
,
Partch AB
,
Monsell SE
,
Valladares O
,
Ellingson SR
,
Wilfred BR
,
Naj AC
,
Wang L-S
,
Kukull WA
et al.
. 2015.
Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.
.
J Neuropathol Exp Neurol. 74(1):75-84.
2014
Naj AC
,
Jun G
,
Reitz C
,
Kunkle BW
,
Perry W
,
Park YSon
,
Beecham GW
,
Rajbhandary RA
,
Hamilton-Nelson KL
,
Wang L-S
et al.
. 2014.
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
.
JAMA Neurol. 71(11):1394-404.
Beecham GW
,
Hamilton K
,
Naj AC
,
Martin ER
,
Huentelman M
,
Myers AJ
,
Corneveaux JJ
,
Hardy J
,
Vonsattel J-P
,
Younkin SG
et al.
. 2014.
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
.
PLoS Genet. 10(9):e1004606.
Logue MW
,
Schu M
,
Vardarajan BN
,
Farrell J
,
Bennett DA
,
Buxbaum JD
,
Byrd GS
,
Ertekin-Taner N
,
Evans D
,
Foroud T
et al.
. 2014.
Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
.
Alzheimers Dement. 10(6):609-618.e11.
2013
Lambert JC
,
Ibrahim-Verbaas CA
,
Harold D
,
Naj AC
,
Sims R
,
Bellenguez C
,
DeStafano AL
,
Bis JC
,
Beecham GW
,
Grenier-Boley B
et al.
. 2013.
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
.
Nat Genet. 45(12):1452-8.
Reitz C
,
Jun G
,
Naj A
,
Rajbhandary R
,
Vardarajan BNarayan
,
Wang L-S
,
Valladares O
,
Lin C-F
,
Larson EB
,
Graff-Radford NR
et al.
. 2013.
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.
.
JAMA. 309(14):1483-92.
2011
Naj AC
,
Jun G
,
Beecham GW
,
Wang L-S
,
Vardarajan BNarayan
,
Buros J
,
Gallins PJ
,
Buxbaum JD
,
Jarvik GP
,
Crane PK
et al.
. 2011.
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
.
Nat Genet. 43(5):436-41.
2010
Li G
,
Shofer JB
,
Rhew IC
,
Kukull WA
,
Peskind ER
,
McCormick W
,
Bowen JD
,
Schellenberg GD
,
Crane PK
,
Breitner JCS
et al.
. 2010.
Age-varying association between statin use and incident Alzheimer's disease.
.
J Am Geriatr Soc. 58(7):1311-7.
Jun G
,
Naj AC
,
Beecham GW
,
Wang L-S
,
Buros J
,
Gallins PJ
,
Buxbaum JD
,
Ertekin-Taner N
,
M Fallin D
,
Friedland R
et al.
. 2010.
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
.
Arch Neurol. 67(12):1473-84.