ADGC Publications

Found 241 results
2023
Chung J, Sahelijo N, Maruyama T, Hu J, Panitch R, Xia W, Mez J, Stein TD, Saykin AJ, Takeyama H et al..  2023.  Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles.. Alzheimers Dement.
Zhang Y, Liu X, Wiggins KL, Kurniansyah N, Guo X, Rodrigue AL, Zhao W, Yanek LR, Ratliff SM, Pitsillides A et al..  2023.  Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts.. Neurology. 100(18):e1930-e1943.
Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D et al..  2023.  Clonal hematopoiesis is associated with protection from Alzheimer's disease.. Nat Med. 29(7):1662-1670.
Tejeda M, Farrell J, Zhu C, Wetzler L, Lunetta KL, Bush WS, Martin ER, San Wang L-, Schellenberg GD, Pericak-Vance MA et al..  2023.  DNA from multiple viral species is associated with Alzheimer's disease risk.. Alzheimers Dement.
Ray NR, Ayodele T, Jean-Francois M, Baez P, Fernandez V, Bradley J, Crane PK, Dalgard CL, Kuzma A, Nicaretta H et al..  2023.  The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology.. Alzheimers Dement.
Gao XRaymond, Chiariglione M, Qin K, Nuytemans K, Scharre DW, Li Y-J, Martin ER.  2023.  Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer's disease prediction.. Sci Rep. 13(1):450.
Kang M, Ang TFang Alvin, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi S-E et al..  2023.  A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.. Mol Neurodegener. 18(1):40.
Bai H, Naj AC, Benchek P, Dumitrescu L, Hohman T, Hamilton-Nelson K, Kallianpur AR, Griswold AJ, Vardarajan B, Martin ER et al..  2023.  A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.. Alzheimers Dement.
Lee Y, Park JYoung, Lee JJae, Gim J, Do ARa, Jo J, Park J, Kim K, Park K, Jin H et al..  2023.  Heritability of cognitive abilities and regional brain structures in middle-aged to elderly East Asians.. Cereb Cortex. 33(10):6051-6062.
Li Y-J, Nuytemans K, La JOk, Jiang R, Slifer SH, Sun S, Naj A, Gao XRaymond, Martin ER.  2023.  Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses.. Alzheimers Dement. 19(7):3148-3157.
Fan KH, Francis L, M Aslam M, Bedison MA, Lawrence E, Acharya V, Snitz BE, Ganguli M, DeKosky ST, Lopez OL et al..  2023.  Investigation of the independent role of a rare APOE variant (L28P; APOE*4Pittsburgh) in late-onset Alzheimer disease.. Neurobiol Aging. 122:107-111.
Li D, Farrell JJ, Mez J, Martin ER, Bush WS, Ruiz A, Boada M, de Rojas I, Mayeux R, Haines JL et al..  2023.  Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.. Alzheimers Dement.
Marini S, Chung J, Han X, Sun X, Parodi L, Farrer LA, Rosand J, Romero JRafael, Anderson CD.  2023.  Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations.. Int J Stroke. 18(7):804-811.
2022
Rajabli F, Tosto G, Hamilton-Nelson KL, Kunkle BW, Vardarajan BN, Naj A, Whitehead PG, Gardner OK, Bush WS, Sariya S et al..  2022.  Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.. Alzheimers Dement.
Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, J Gaziano M, Harrington KM et al..  2022.  African ancestry GWAS of dementia in a large military cohort identifies significant risk loci.. Mol Psychiatry.
Kuksa PP, Liu C-L, Fu W, Qu L, Zhao Y, Katanic Z, Clark K, Kuzma AB, Ho P-C, Tzeng K-T et al..  2022.  Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.. J Alzheimers Dis. 86(1):461-477.
Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A et al..  2022.  Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.. Mov Disord. 37(10):2110-2121.
Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N et al..  2022.  Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.. Nat Genet. 54(12):1786-1794.
Chung J, Das A, Sun X, Sobreira DR, Leung YYee, Igartua C, Mozaffari S, Chou Y-F, Thiagalingam S, Mez J et al..  2022.  Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.. Alzheimers Dement.
Shade LMp, Katsumata Y, Hohman TJ, Nho K, Saykin AJ, Mukherjee S, Boehme KL, Kauwe JSk, Farrer LA, Schellenberg GD et al..  2022.  Genome-wide association study of brain arteriolosclerosis.. J Cereb Blood Flow Metab. 42(8):1437-1450.
Rajabli F, Beecham GW, Hendrie HC, Baiyewu O, Ogunniyi A, Gao S, Kushch NA, Lipkin-Vasquez M, Hamilton-Nelson KL, Young JI et al..  2022.  A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.. PLoS Genet. 18(7):e1009977.
Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW et al..  2022.  Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.. Sci Rep. 12(1):6117.
Romero-Molina C, Garretti F, Andrews SJ, Marcora E, Goate AM.  2022.  Microglial efferocytosis: Diving into the Alzheimer's disease gene pool.. Neuron. 110(21):3513-3533.
Katsumata Y, Shade LM, Hohman TJ, Schneider JA, Bennett DA, Farfel JM, Kukull WA, Fardo DW, Nelson PT.  2022.  Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.. Neurobiol Dis. 174:105880.
Godrich D, Martin ER, Schellenberg G, Pericak-Vance MA, Cuccaro M, Scott WK, Kukull W, Montine T, Beecham GW.  2022.  Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population.. Alzheimers Dement. 18(12):2403-2412.

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