ADGC Publications

Found 248 results
2013
Ryvkin P, Leung YYee, Silverman IM, Childress M, Valladares O, Dragomir I, Gregory BD, San Wang L-.  2013.  HAMR: high-throughput annotation of modified ribonucleotides.. RNA. 19(12):1684-92.
Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD et al..  2013.  Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).. Transl Psychiatry. 3:e256.
Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, J Gibbs R, Mayeux R, Haines JL et al..  2013.  Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.. Ann Hum Genet. 77(2):85-105.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B et al..  2013.  Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.. Nat Genet. 45(12):1452-8.
Kohli MA, John-Williams K, Rajbhandary R, Naj A, Whitehead P, Hamilton K, Carney RM, Wright C, Crocco E, Gwirtzman HE et al..  2013.  Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians.. Neurobiol Aging. 34(5):1519.e5-12.
Miyashita A, Koike A, Jun G, Wang L-S, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H et al..  2013.  SORL1 Is Genetically Associated with Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians.. PLoS One. 8(4):e58618.
Reitz C, Mayeux R.  2013.  TREM2 and neurodegenerative disease.. N Engl J Med. 369(16):1564-5.
Stutzbach LD, Xie SX, Naj AC, Albin R, Gilman S, M Y Lee V, Trojanowski JQ, Devlin B, Schellenberg GD.  2013.  The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.. Acta Neuropathol Commun. 1:31.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BNarayan, Wang L-S, Valladares O, Lin C-F, Larson EB, Graff-Radford NR et al..  2013.  Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.. JAMA. 309(14):1483-92.
Schafer CM, Campbell NG, Cai G, Yu F, Makarov V, Yoon S, Daly MJ, Gibbs RA, Schellenberg GD, Devlin B et al..  2013.  Whole exome sequencing reveals minimal differences between cell line and whole blood derived DNA.. Genomics. 102(4):270-7.
2012
Zou F, Chai HSeng, Younkin CS, Allen M, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.. PLoS Genet. 8(6):e1002707.
Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS et al..  2012.  Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.. Nat Genet. 44(12):1349-54.
Jun G, Vardarajan BN, Buros J, Yu C-E, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL et al..  2012.  Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.. Arch Neurol. 69(10):1270-9.
Coppola G, Chinnathambi S, Lee JJiYong, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R et al..  2012.  Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.. Hum Mol Genet. 21(15):3500-12.
Majounie E, Renton AE, Mok K, Dopper EGP, Waite A, Rollinson S, Chiò A, Restagno G, Nicolaou N, Simon-Sanchez J et al..  2012.  Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study.. Lancet Neurol. 11(4):323-30.
Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA et al..  2012.  GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.. Neurology. 79(19):1944-50.
Schellenberg GD, Montine TJ.  2012.  The genetics and neuropathology of Alzheimer's disease.. Acta Neuropathol. 124(3):305-23.
Barral S, Bird T, Goate A, Farlow MR, Diaz-Arrastia R, Bennett DA, Graff-Radford N, Boeve BF, Sweet RA, Stern Y et al..  2012.  Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.. Neurology. 78(19):1464-71.
Vardarajan BN, Bruesegem SY, Harbour ME, Inzelberg R, Friedland R, St George-Hyslop P, Seaman MNJ, Farrer LA.  2012.  Identification of Alzheimer disease-associated variants in genes that regulate retromer function.. Neurobiol Aging. 33(9):2231.e15-2231.e30.
Liu N, Landreh M, Cao K, Abe M, Hendriks G-J, Kennerdell JR, Zhu Y, Wang L-S, Bonini NM.  2012.  The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila.. Nature. 482(7386):519-23.
Allen M, Zou F, Chai HSeng, Younkin CS, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Novel late-onset Alzheimer disease loci variants associate with brain gene expression.. Neurology. 79(3):221-8.
Ramanan VK, Shen L, Moore JH, Saykin AJ.  2012.  Pathway analysis of genomic data: concepts, methods, and prospects for future development.. Trends Genet. 28(7):323-32.
2011
Kohen R, Shofer JB, Korvatska O, Petrie EC, Wang LY, Schellenberg GD, Peskind ER, Wilkinson CW.  2011.  ABCB1 genotype and CSF beta-amyloid in Alzheimer disease.. J Geriatr Psychiatry Neurol. 24(2):63-6.
Bekris LM, Galloway NM, Millard S, Lockhart D, Li G, Galasko DR, Farlow MR, Clark CM, Quinn JF, Kaye JA et al..  2011.  Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease.. Neurobiol Aging. 32(3):556.e13-23.
Bailey M, Kauwe JSK, Cruchaga C, McKean D, Mayo K, Bertlesen S, Hinrichs A, Fagan A, Holtzman D, Goate AM.  2011.  Association study of recently reported AD risk variants with cerebrospinal fluid AD biomarker levels. AAIC (ICAD) 2011, Paris, France.

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