ADGC Publications

Found 25 results
Filters: Author is Kunkle, Brian W  [Clear All Filters]
2024
Yan D, Hu B, Darst BF, Mukherjee S, Kunkle BW, Deming Y, Dumitrescu L, Wang Y, Naj A, Kuzma A et al..  2024.  Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes.. Elife. 12
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Qiao M, Vardarajan BN, Cosacak MI, Kizil C, Jean-Francois M et al..  2024.  Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.. Alzheimers Dement. 20(8):5247-5261.
Zhang X, Gomez L, Below JE, Naj AC, Martin ER, Kunkle BW, Bush WS.  2024.  An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer's Disease.. J Alzheimers Dis. 98(3):1053-1067.
2022
Rajabli F, Tosto G, Hamilton-Nelson KL, Kunkle BW, Vardarajan BN, Naj A, Whitehead PG, Gardner OK, Bush WS, Sariya S et al..  2022.  Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.. Alzheimers Dement.
Chung J, Das A, Sun X, Sobreira DR, Leung YYee, Igartua C, Mozaffari S, Chou Y-F, Thiagalingam S, Mez J et al..  2022.  Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.. Alzheimers Dement.
Rajabli F, Beecham GW, Hendrie HC, Baiyewu O, Ogunniyi A, Gao S, Kushch NA, Lipkin-Vasquez M, Hamilton-Nelson KL, Young JI et al..  2022.  A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.. PLoS Genet. 18(7):e1009977.
Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW et al..  2022.  Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.. Sci Rep. 12(1):6117.
2021
Kunkle BW, Schmidt M, Klein H-U, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD et al..  2021.  Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.. JAMA Neurol. 78(1):102-113.
2020
Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ et al..  2020.  Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.. Cell Rep. 32(9):108091.
2019
Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW et al..  2019.  Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.. JAMA Neurol. 76:(9):1099-1108.
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE et al..  2019.  Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Mol Psychiatry.
Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R et al..  2019.  CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.. Aging Cell. 18(4):e12964.
Hu Y, Li M, Lu Q, Weng H, Wang J, Zekavat SM, Yu Z, Li B, Gu J, Muchnik S et al..  2019.  A Statistical Framework for Cross-tissue Transcriptome-wide Association Analysis.. Nat Genet. 51(3):568-576.
2018
Rajabli F, Feliciano BE, Celis K, Hamilton-Nelson KL, Whitehead PL, Adams LD, Bussies PL, Manrique CP, Rodriguez A, Rodriguez V et al..  2018.  Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.. PLoS Genet. 14(12):e1007791.
Naj AC, Lin H, Vardarajan BN, White S, Lancour D, Ma Y, Schmidt M, Sun F, Butkiewicz M, Bush WS et al..  2018.  Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project.. Genomics.
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE et al..  2018.  Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.. Mol Psychiatry.
2017
Kunkle BW, Vardarajan BN, Naj AC, Whitehead PL, Rolati S, Slifer S, Carney RM, Cuccaro ML, Vance JM, Gilbert JR et al..  2017.  Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.. JAMA Neurol. 74(9):1113-1122.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK et al..  2017.  Transethnic genome-wide scan identifies novel Alzheimer's disease loci.. Alzheimers Dement. 13(7):727-738.
2016
Cukier HN, Kunkle BW, Vardarajan BN, Rolati S, Hamilton-Nelson KL, Kohli MA, Whitehead PL, Dombroski BA, Van Booven D, Lang R et al..  2016.  ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.. Neurol Genet. 2(3):e79.
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD et al..  2016.  Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.. Neurobiol Aging. 38:141-150.
Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH et al..  2016.  Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.. Alzheimers Dement. 12(1):2-10.
Kohli MA, Cukier HN, Hamilton-Nelson KL, Rolati S, Kunkle BW, Whitehead PL, Züchner SL, Farrer LA, Martin ER, Beecham GW et al..  2016.  Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease.. Neurol Genet. 2(1):e41.
2015
Wang L-S, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JDGonzalez, Cannon-Albright L, Baldwin CT, Zetterberg H et al..  2015.  Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA Neurol. 72(2):209-16.
2014
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YSon, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang L-S et al..  2014.  Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.. JAMA Neurol. 71(11):1394-404.
Carney RM, Kohli MA, Kunkle BW, Naj AC, Gilbert JR, Züchner S, Pericak-Vance MA.  2014.  Parkinsonism and distinct dementia patterns in a family with the MAPT R406W mutation.. Alzheimers Dement. 10(3):360-5.