ADGC Publications

Found 82 results
Filters: Keyword is Genome-Wide Association Study  [Clear All Filters]
2024
Yan D, Hu B, Darst BF, Mukherjee S, Kunkle BW, Deming Y, Dumitrescu L, Wang Y, Naj A, Kuzma A et al..  2024.  Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes.. Elife. 12
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Qiao M, Vardarajan BN, Cosacak MI, Kizil C, Jean-Francois M et al..  2024.  Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.. Alzheimers Dement. 20(8):5247-5261.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK et al..  2024.  Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.. Alzheimers Dement. 20(4):2670-2679.
Zhang X, Gomez L, Below JE, Naj AC, Martin ER, Kunkle BW, Bush WS.  2024.  An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer's Disease.. J Alzheimers Dis. 98(3):1053-1067.
2023
Kang M, Ang TFang Alvin, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi S-E et al..  2023.  A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.. Mol Neurodegener. 18(1):40.
Li Y-J, Nuytemans K, La JOk, Jiang R, Slifer SH, Sun S, Naj A, Gao XRaymond, Martin ER.  2023.  Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses.. Alzheimers Dement. 19(7):3148-3157.
Marini S, Chung J, Han X, Sun X, Parodi L, Farrer LA, Rosand J, Romero JRafael, Anderson CD.  2023.  Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations.. Int J Stroke. 18(7):804-811.
2022
Kuksa PP, Liu C-L, Fu W, Qu L, Zhao Y, Katanic Z, Clark K, Kuzma AB, Ho P-C, Tzeng K-T et al..  2022.  Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.. J Alzheimers Dis. 86(1):461-477.
Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A et al..  2022.  Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.. Mov Disord. 37(10):2110-2121.
Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N et al..  2022.  Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.. Nat Genet. 54(12):1786-1794.
Shade LMp, Katsumata Y, Hohman TJ, Nho K, Saykin AJ, Mukherjee S, Boehme KL, Kauwe JSk, Farrer LA, Schellenberg GD et al..  2022.  Genome-wide association study of brain arteriolosclerosis.. J Cereb Blood Flow Metab. 42(8):1437-1450.
Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW et al..  2022.  Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.. Sci Rep. 12(1):6117.
Romero-Molina C, Garretti F, Andrews SJ, Marcora E, Goate AM.  2022.  Microglial efferocytosis: Diving into the Alzheimer's disease gene pool.. Neuron. 110(21):3513-3533.
Katsumata Y, Shade LM, Hohman TJ, Schneider JA, Bennett DA, Farfel JM, Kukull WA, Fardo DW, Nelson PT.  2022.  Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.. Neurobiol Dis. 174:105880.
Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W, Bennett DA, Foroud TM et al..  2022.  Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease.. Alzheimers Dement. 18(11):2042-2054.
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SEun, Bush WS, Engelman CD et al..  2022.  Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.. Brain. 145(7):2541-2554.
2021
Chen H-H, Petty LE, Sha J, Zhao Y, Kuzma A, Valladares O, Bush W, Naj AC, Gamazon ER, Below JE.  2021.  Genetically regulated expression in late-onset Alzheimer's disease implicates risk genes within known and novel loci.. Transl Psychiatry. 11(1):618.
Kunkle BW, Schmidt M, Klein H-U, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD et al..  2021.  Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.. JAMA Neurol. 78(1):102-113.
2020
Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ et al..  2020.  Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.. Cell Rep. 32(9):108091.
Sherva R, Gross A, Mukherjee S, Koesterer R, Amouyel P, Bellenguez C, Dufouil C, Bennett DA, Chibnik L, Cruchaga C et al..  2020.  Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.. Alzheimers Dement. 16(8):1134-1145.
2019
Patel D, Mez J, Vardarajan BN, Staley L, Chung J, Zhang X, Farrell JJ, Rynkiewicz MJ, Cannon-Albright LA, Teerlink CC et al..  2019.  Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.. JAMA Netw Open. 2(3):e191350.
Baker E, Sims R, Leonenko G, Frizzati A, Harwood JC, Grozeva D, Morgan K, Passmore P, Holmes C, Powell J et al..  2019.  Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.. PLoS One. 14(7):e0218111.
Hu Y, Li M, Lu Q, Weng H, Wang J, Zekavat SM, Yu Z, Li B, Gu J, Muchnik S et al..  2019.  A Statistical Framework for Cross-tissue Transcriptome-wide Association Analysis.. Nat Genet. 51(3):568-576.
2018
Rajabli F, Feliciano BE, Celis K, Hamilton-Nelson KL, Whitehead PL, Adams LD, Bussies PL, Manrique CP, Rodriguez A, Rodriguez V et al..  2018.  Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.. PLoS Genet. 14(12):e1007791.
Bonham LW, Karch CM, Fan CC, Tan C, Geier EG, Wang Y, Wen N, Broce IJ, Li Y, Barkovich MJ et al..  2018.  CXCR4 involvement in neurodegenerative diseases.. Transl Psychiatry. 8(1):73.

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