ADGC Publications

Found 248 results
2024
Lei Y, Naj AChristian, Xu H, Li R, Chen Y.  2024.  Balancing the efforts of chart review and gains in PRS prediction accuracy: An empirical study.. J Biomed Inform. 157:104705.
Yan D, Hu B, Darst BF, Mukherjee S, Kunkle BW, Deming Y, Dumitrescu L, Wang Y, Naj A, Kuzma A et al..  2024.  Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes.. Elife. 12
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Qiao M, Vardarajan BN, Cosacak MI, Kizil C, Jean-Francois M et al..  2024.  Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.. Alzheimers Dement. 20(8):5247-5261.
Antonsdottir IMargret, Creese B, Klei L, DeMichele-Sweet MAnn A, Weamer EA, Garcia-Gonzalez P, Marquie M, Boada M, Alarcón-Martín E, Valero S et al..  2024.  Genetic associations with psychosis and affective disturbance in Alzheimer's disease.. Alzheimers Dement (N Y). 10(2):e12472.
Belloy ME, Le Guen Y, Stewart I, Herz J, Sherva R, Zhang R, Merritt V, Panizzon MS, Hauger RL, J Gaziano M et al..  2024.  The Role of X Chromosome in Alzheimer's Disease Genetics.. medRxiv.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK et al..  2024.  Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.. Alzheimers Dement. 20(4):2670-2679.
Zhang X, Gomez L, Below JE, Naj AC, Martin ER, Kunkle BW, Bush WS.  2024.  An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer's Disease.. J Alzheimers Dis. 98(3):1053-1067.
2023
Chung J, Sahelijo N, Maruyama T, Hu J, Panitch R, Xia W, Mez J, Stein TD, Saykin AJ, Takeyama H et al..  2023.  Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles.. Alzheimers Dement.
Zhang Y, Liu X, Wiggins KL, Kurniansyah N, Guo X, Rodrigue AL, Zhao W, Yanek LR, Ratliff SM, Pitsillides A et al..  2023.  Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function: A Meta-analysis of Community-Based Cohorts.. Neurology. 100(18):e1930-e1943.
Bouzid H, Belk JA, Jan M, Qi Y, Sarnowski C, Wirth S, Ma L, Chrostek MR, Ahmad H, Nachun D et al..  2023.  Clonal hematopoiesis is associated with protection from Alzheimer's disease.. Nat Med. 29(7):1662-1670.
Tejeda M, Farrell J, Zhu C, Wetzler L, Lunetta KL, Bush WS, Martin ER, San Wang L-, Schellenberg GD, Pericak-Vance MA et al..  2023.  DNA from multiple viral species is associated with Alzheimer's disease risk.. Alzheimers Dement.
Ray NR, Ayodele T, Jean-Francois M, Baez P, Fernandez V, Bradley J, Crane PK, Dalgard CL, Kuzma A, Nicaretta H et al..  2023.  The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology.. Alzheimers Dement.
Gao XRaymond, Chiariglione M, Qin K, Nuytemans K, Scharre DW, Li Y-J, Martin ER.  2023.  Explainable machine learning aggregates polygenic risk scores and electronic health records for Alzheimer's disease prediction.. Sci Rep. 13(1):450.
Kang M, Ang TFang Alvin, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi S-E et al..  2023.  A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores.. Mol Neurodegener. 18(1):40.
Bai H, Naj AC, Benchek P, Dumitrescu L, Hohman T, Hamilton-Nelson K, Kallianpur AR, Griswold AJ, Vardarajan B, Martin ER et al..  2023.  A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.. Alzheimers Dement.
Lee Y, Park JYoung, Lee JJae, Gim J, Do ARa, Jo J, Park J, Kim K, Park K, Jin H et al..  2023.  Heritability of cognitive abilities and regional brain structures in middle-aged to elderly East Asians.. Cereb Cortex. 33(10):6051-6062.
Li Y-J, Nuytemans K, La JOk, Jiang R, Slifer SH, Sun S, Naj A, Gao XRaymond, Martin ER.  2023.  Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses.. Alzheimers Dement. 19(7):3148-3157.
Fan KH, Francis L, M Aslam M, Bedison MA, Lawrence E, Acharya V, Snitz BE, Ganguli M, DeKosky ST, Lopez OL et al..  2023.  Investigation of the independent role of a rare APOE variant (L28P; APOE*4Pittsburgh) in late-onset Alzheimer disease.. Neurobiol Aging. 122:107-111.
Li D, Farrell JJ, Mez J, Martin ER, Bush WS, Ruiz A, Boada M, de Rojas I, Mayeux R, Haines JL et al..  2023.  Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.. Alzheimers Dement.
Marini S, Chung J, Han X, Sun X, Parodi L, Farrer LA, Rosand J, Romero JRafael, Anderson CD.  2023.  Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations.. Int J Stroke. 18(7):804-811.
2022
Rajabli F, Tosto G, Hamilton-Nelson KL, Kunkle BW, Vardarajan BN, Naj A, Whitehead PG, Gardner OK, Bush WS, Sariya S et al..  2022.  Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.. Alzheimers Dement.
Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, J Gaziano M, Harrington KM et al..  2022.  African ancestry GWAS of dementia in a large military cohort identifies significant risk loci.. Mol Psychiatry.
Kuksa PP, Liu C-L, Fu W, Qu L, Zhao Y, Katanic Z, Clark K, Kuzma AB, Ho P-C, Tzeng K-T et al..  2022.  Alzheimer's Disease Variant Portal: A Catalog of Genetic Findings for Alzheimer's Disease.. J Alzheimers Dis. 86(1):461-477.
Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A et al..  2022.  Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.. Mov Disord. 37(10):2110-2121.
Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N et al..  2022.  Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.. Nat Genet. 54(12):1786-1794.

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