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Found 31 results
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is
Beecham, Gary W
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2024
Ray NR
,
Kunkle BW
,
Hamilton-Nelson K
,
Kurup JT
,
Rajabli F
,
Qiao M
,
Vardarajan BN
,
Cosacak MI
,
Kizil C
,
Jean-Francois M
et al.
. 2024.
Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.
.
Alzheimers Dement. 20(8):5247-5261.
2023
Ray NR
,
Ayodele T
,
Jean-Francois M
,
Baez P
,
Fernandez V
,
Bradley J
,
Crane PK
,
Dalgard CL
,
Kuzma A
,
Nicaretta H
et al.
. 2023.
The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology.
.
Alzheimers Dement.
Bai H
,
Naj AC
,
Benchek P
,
Dumitrescu L
,
Hohman T
,
Hamilton-Nelson K
,
Kallianpur AR
,
Griswold AJ
,
Vardarajan B
,
Martin ER
et al.
. 2023.
A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.
.
Alzheimers Dement.
2022
Rajabli F
,
Tosto G
,
Hamilton-Nelson KL
,
Kunkle BW
,
Vardarajan BN
,
Naj A
,
Whitehead PG
,
Gardner OK
,
Bush WS
,
Sariya S
et al.
. 2022.
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.
.
Alzheimers Dement.
Holstege H
,
Hulsman M
,
Charbonnier C
,
Grenier-Boley B
,
Quenez O
,
Grozeva D
,
van Rooij JGJ
,
Sims R
,
Ahmad S
,
Amin N
et al.
. 2022.
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.
.
Nat Genet. 54(12):1786-1794.
Rajabli F
,
Beecham GW
,
Hendrie HC
,
Baiyewu O
,
Ogunniyi A
,
Gao S
,
Kushch NA
,
Lipkin-Vasquez M
,
Hamilton-Nelson KL
,
Young JI
et al.
. 2022.
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.
.
PLoS Genet. 18(7):e1009977.
Godrich D
,
Martin ER
,
Schellenberg G
,
Pericak-Vance MA
,
Cuccaro M
,
Scott WK
,
Kukull W
,
Montine T
,
Beecham GW
. 2022.
Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population.
.
Alzheimers Dement. 18(12):2403-2412.
2020
Reiman EM
,
Arboleda-Velasquez JF
,
Quiroz YT
,
Huentelman MJ
,
Beach TG
,
Caselli RJ
,
Chen Y
,
Su Y
,
Myers AJ
,
Hardy J
et al.
. 2020.
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
.
Nat Commun. 11(1):667.
2019
Bis JC
,
Jian X
,
Kunkle BW
,
Chen Y
,
Hamilton-Nelson KL
,
Bush WS
,
Salerno WJ
,
Lancour D
,
Ma Y
,
Renton AE
et al.
. 2019.
Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
.
Mol Psychiatry.
Gardner OK
,
Wang L
,
Van Booven D
,
Whitehead PL
,
Hamilton-Nelson KL
,
Adams LD
,
Starks TD
,
Hofmann NK
,
Vance JM
,
Cuccaro ML
et al.
. 2019.
RNA editing alterations in a multi-ethnic Alzheimer disease cohort converge on immune and endocytic molecular pathways.
.
Hum Mol Genet. 28(18):3053-3061.
2018
Rajabli F
,
Feliciano BE
,
Celis K
,
Hamilton-Nelson KL
,
Whitehead PL
,
Adams LD
,
Bussies PL
,
Manrique CP
,
Rodriguez A
,
Rodriguez V
et al.
. 2018.
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
.
PLoS Genet. 14(12):e1007791.
Beecham GW
,
Vardarajan B
,
Blue E
,
Bush W
,
Jaworski J
,
Barral S
,
DeStefano A
,
Hamilton-Nelson K
,
Kunkle B
,
Martin ER
et al.
. 2018.
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
.
Neurol Genet. 4(6):e286.
Bis JC
,
Jian X
,
Kunkle BW
,
Chen Y
,
Hamilton-Nelson KL
,
Bush WS
,
Salerno WJ
,
Lancour D
,
Ma Y
,
Renton AE
et al.
. 2018.
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
.
Mol Psychiatry.
Vardarajan BN
,
Barral S
,
Jaworski J
,
Beecham GW
,
Blue E
,
Tosto G
,
Reyes-Dumeyer D
,
Medrano M
,
Lantigua R
,
Naj A
et al.
. 2018.
Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease.
.
Ann Clin Transl Neurol. 5(4):406-417.
2017
Beecham GW
,
Bis JC
,
Martin ER
,
Choi S-H
,
Destefano AL
,
van Duijn CM
,
Fornage M
,
Gabriel SB
,
Koboldt DC
,
Larson DE
et al.
. 2017.
The Alzheimer's Disease Sequencing Project: Study design and sample selection.
.
Neurol Genet. 3(5):e194.
Kunkle BW
,
Vardarajan BN
,
Naj AC
,
Whitehead PL
,
Rolati S
,
Slifer S
,
Carney RM
,
Cuccaro ML
,
Vance JM
,
Gilbert JR
et al.
. 2017.
Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport.
.
JAMA Neurol. 74(9):1113-1122.
Jun GR
,
Chung J
,
Mez J
,
Barber R
,
Beecham GW
,
Bennett DA
,
Buxbaum JD
,
Byrd GS
,
Carrasquillo MM
,
Crane PK
et al.
. 2017.
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
.
Alzheimers Dement. 13(7):727-738.
2016
Cukier HN
,
Kunkle BW
,
Vardarajan BN
,
Rolati S
,
Hamilton-Nelson KL
,
Kohli MA
,
Whitehead PL
,
Dombroski BA
,
Van Booven D
,
Lang R
et al.
. 2016.
ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.
.
Neurol Genet. 2(3):e79.
Mez J
,
Mukherjee S
,
Thornton T
,
Fardo DW
,
Trittschuh E
,
Sutti S
,
Sherva R
,
Kauwe JS
,
Naj AC
,
Beecham GW
et al.
. 2016.
The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
.
Neurobiol Aging. 41:115-121.
Kunkle BW
,
Jaworski J
,
Barral S
,
Vardarajan B
,
Beecham GW
,
Martin ER
,
Cantwell LS
,
Partch A
,
Bird TD
,
Raskind WH
et al.
. 2016.
Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease.
.
Alzheimers Dement. 12(1):2-10.
Hohman TJ
,
Cooke-Bailey JN
,
Reitz C
,
Jun G
,
Naj A
,
Beecham GW
,
Liu Z
,
Carney RM
,
Vance JM
,
Cuccaro ML
et al.
. 2016.
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
.
Alzheimers Dement. 12(3):233-43.
Kohli MA
,
Cukier HN
,
Hamilton-Nelson KL
,
Rolati S
,
Kunkle BW
,
Whitehead PL
,
Züchner SL
,
Farrer LA
,
Martin ER
,
Beecham GW
et al.
. 2016.
Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease.
.
Neurol Genet. 2(1):e41.
2015
Beecham GW
,
Dickson DW
,
Scott WK
,
Martin ER
,
Schellenberg GD
,
Nuytemans K
,
Larson EB
,
Buxbaum JD
,
Trojanowski JQ
,
Van Deerlin VM
et al.
. 2015.
PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.
.
Neurology. 84(10):972-80.
Wang L-S
,
Naj AC
,
Graham RR
,
Crane PK
,
Kunkle BW
,
Cruchaga C
,
Murcia JDGonzalez
,
Cannon-Albright L
,
Baldwin CT
,
Zetterberg H
et al.
. 2015.
Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
.
JAMA Neurol. 72(2):209-16.
2014
Naj AC
,
Jun G
,
Reitz C
,
Kunkle BW
,
Perry W
,
Park YSon
,
Beecham GW
,
Rajbhandary RA
,
Hamilton-Nelson KL
,
Wang L-S
et al.
. 2014.
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
.
JAMA Neurol. 71(11):1394-404.
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