ADGC Publications

Found 71 results
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2013
McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA et al..  2013.  Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records.. PLoS One. 8(6):e63481.
Hibar DP, Stein JL, Ryles AB, Kohannim O, Jahanshad N, Medland SE, Hansell NK, McMahon KL, de Zubicaray GI, Montgomery GW et al..  2013.  Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.. Brain Imaging Behav. 7(2):102-15.
Cruchaga C, Kauwe JSK, Harari O, Jin SChih, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D et al..  2013.  GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.. Neuron. 78(2):256-68.
Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD et al..  2013.  Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).. Transl Psychiatry. 3:e256.
Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, J Gibbs R, Mayeux R, Haines JL et al..  2013.  Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.. Ann Hum Genet. 77(2):85-105.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B et al..  2013.  Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.. Nat Genet. 45(12):1452-8.
Stutzbach LD, Xie SX, Naj AC, Albin R, Gilman S, M Y Lee V, Trojanowski JQ, Devlin B, Schellenberg GD.  2013.  The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease.. Acta Neuropathol Commun. 1:31.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BNarayan, Wang L-S, Valladares O, Lin C-F, Larson EB, Graff-Radford NR et al..  2013.  Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.. JAMA. 309(14):1483-92.
2012
Zou F, Chai HSeng, Younkin CS, Allen M, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.. PLoS Genet. 8(6):e1002707.
Jun G, Vardarajan BN, Buros J, Yu C-E, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL et al..  2012.  Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.. Arch Neurol. 69(10):1270-9.
Schellenberg GD, Montine TJ.  2012.  The genetics and neuropathology of Alzheimer's disease.. Acta Neuropathol. 124(3):305-23.
Barral S, Bird T, Goate A, Farlow MR, Diaz-Arrastia R, Bennett DA, Graff-Radford N, Boeve BF, Sweet RA, Stern Y et al..  2012.  Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.. Neurology. 78(19):1464-71.
Allen M, Zou F, Chai HSeng, Younkin CS, Crook J, V Pankratz S, Carrasquillo MM, Rowley CN, Nair AA, Middha S et al..  2012.  Novel late-onset Alzheimer disease loci variants associate with brain gene expression.. Neurology. 79(3):221-8.
2011
Kohen R, Shofer JB, Korvatska O, Petrie EC, Wang LY, Schellenberg GD, Peskind ER, Wilkinson CW.  2011.  ABCB1 genotype and CSF beta-amyloid in Alzheimer disease.. J Geriatr Psychiatry Neurol. 24(2):63-6.
Bekris LM, Galloway NM, Millard S, Lockhart D, Li G, Galasko DR, Farlow MR, Clark CM, Quinn JF, Kaye JA et al..  2011.  Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease.. Neurobiol Aging. 32(3):556.e13-23.
Naj AC, Jun G, Beecham GW, Wang L-S, Vardarajan BNarayan, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK et al..  2011.  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.. Nat Genet. 43(5):436-41.
Höglinger GU, Melhem NM, Dickson DW, Sleiman PMA, San Wang L-, Klei L, Rademakers R, de Silva R, Litvan I, Riley DE et al..  2011.  Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.. Nat Genet. 43(7):699-705.
Sherva R, Farrer LA.  2011.  Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease.. Curr Psychiatry Rep. 13(2):138-46.
2010
Van Deerlin VM, Sleiman PMA, Martinez-Lage M, Chen-Plotkin A, San Wang L-, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M et al..  2010.  Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.. Nat Genet. 42(3):234-9.
Han M-R, Schellenberg GD, San Wang L-.  2010.  Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.. BMC Neurol. 10:90.
Jun G, Naj AC, Beecham GW, Wang L-S, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, M Fallin D, Friedland R et al..  2010.  Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.. Arch Neurol. 67(12):1473-84.

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